催产素在孤独症患者社交障碍中的作用及治疗潜能(综述)

Role and therapeutic potential of oxytocin in autistic patients' social impairments(Review)

孤独症是一种原因不明的广泛性神经发育障碍性疾病,至今尚无有效的治疗方法。作为孤独症的特征性症状之一,社交障碍严重影响患者的身心健康与生活质量。研究显示,催产素在社会交往中发挥重要作用,而催产素缺乏或利用不足可能与孤独症患者的社交障碍有关。本文总结了近年来关于催产素与孤独症社交障碍的研究进展,并提出催产素用于孤独症临床治疗的可能性,希望能够对孤独症的研究和治疗提供帮助。

Autism is a pervasive neurodevelopmental disorders with an unexplained etiology, and absence of effective therapentic mean. As a characteristic symptom of autism, social impairments seriously affect the patients＇ health and life. It was shown that oxytocin plays an important role in social interaction, and the lack or underutiliza- tion of oxytocin may be associated with the social impairments of autism patients. In this paper, We summarrized re- cent studies on oxytocin and social impairments in autism, and proposed the possibilities of oxytocin for the clinical treatment of autism, hoping that it would be helpful for the research and treatment of autism.