摘要
肿瘤细胞对蛋白质水平的要求异于正常细胞,蛋白酶抑制剂类药物对肿瘤细胞生长有明显抑制作用,并且对免疫类与炎症类疾病颇具疗效。对各种蛋白酶抑制剂类新药进行了评述,重点介绍了硼替佐米的结构、性质和合成。
The requirements of proteins between normal and tumor cells are different.Researches suggest that protease inhibitor drugs can inhibit the growth of tumor cells significantly,and have good effect on the immune and inflammatory diseases as well.This article gives an introduction about the protease inhibitor drugs,with special attention to one new kind of medicine——bortezomib.
出处
《化学与生物工程》
CAS
2011年第6期7-11,共5页
Chemistry & Bioengineering
基金
山东省自然科学基金资助项目(2009ZRB01220)
