中医食疗对侵蚀性葡萄胎化疗患者的影响

Effect of TCM Diet Therapy on Chemotherapy of Patients with Invasive Hydatidiform Mole

目的探讨中医食疗对侵蚀性葡萄胎化疗患者的影响。方法对侵蚀性葡萄胎行化疗患者80例,按住院号码的单双号随机分为干预组和对照组各40例,对照组接受常规的评估、健康教育及饮食指导,干预组在对照组基础上给予中医食疗,观察两组患者化疗不同时间血象及所出现化疗不良反应的情况。结果干预组与对照组的白细胞、中性粒细胞比例、红细胞计数、血红蛋白、红细胞压积、血小板计数在化疗前1～2 d比较差异无统计学意义(P>0.05),但在化疗结束第1周及第2周两组患者比较,干预组各血象指标明显比对照组好,差异有统计学意义(P<0.05);干预组化疗出现的恶心、呕吐、口腔黏膜炎、腹泻、腹痛不良反应较对照组明显减少,差异有统计学意义(P<0.05)。结论中医食疗应用于侵蚀性葡萄胎化疗患者能显著提高其外周血象恢复,并减少化疗所致不良反应的发生。

Objective To explore the effect of TCM diet therapy on chemotherapy of patients suffered from invasive hydatidiform mole.Methods 80 patients with invasive hydatidiform mole undergoing chemotherapy were randomly divided into experiment group（n=40） and control group（n=40）.Patients in control group were provided routine nursing,health education and diet guidance but patients in experiment group were treated with TCM diet therapy in addition.Results There was no statistic difference of the comparison of leukocytes,the proportion of neutrophilic leukocyte,erythrocyte counting,hemoglobin,hematocrit and platelet counting 1～2 d before chemotherapy（P〉0.05）,while the comparison among these items indicated statistic significance 1 week and 2 weeks after the chemotherapy（P〈0.05）.And less adverse reactions occurred in patients in experiment group（P〈0.05）.Conclusion TCM diet therapy can relieve adverse reaction of chemotherapy of patients with invasive hydatidiform mole evidently.