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重型肝炎患者血浆置换治疗前后凝血功能变化的研究 被引量:4

The change of blood coagulant function for hepatitis patients treated by plasma exchange
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摘要 目的观察重型肝炎患者采用血浆置换治疗前后凝血功能的变化情况。方法 46例重型肝病患者在综合治疗的基础上经血浆置换,通过观察凝血功能的变化,判断分析血浆置换治疗重型肝炎的临床疗效。结果经血浆置换治疗后凝血酶原时间(PT)、部分凝血酶原激活时间(APTT)、凝血酶原凝固时间(TT)均有不同程度的缩短(P<0.05),纤维蛋白原(Fib)无显著改变(P>0.05)。结论在综合治疗的基础上血浆置换是治疗重型肝病一种有效的手段。 Objective To explore the effects of blood coagulant function on fulminant hepatitis patients treated by plasma exchange. Methods 46 fulminant hepatitis patients were treated by plasma exchange based on multi-modality treatment. To examine the change of blood coagulant function,the clinical efficacy of fulminant hepatitis patients was evaluated. Results After plasma exchange treatment,prothrombin time.activated partial thromboplastin time(APTT), thrombin time(TT)was reduced in various degree. Conclusion Plasma exchange based on multi modality treatment was an effective therapy method for fulminant hepatitis.
出处 《国际检验医学杂志》 CAS 2011年第9期961-961,966,共2页 International Journal of Laboratory Medicine
关键词 血浆置换 肝病 凝血功能 plasma exchange liver diseases blood coagulant function
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  • 1Montejo Gonzalez JC,Catalan Gonzalez M, Meneu Diaz JC, et al. Artificial liver support system in acute liver failure patients waiting liver transplantation [J].Hepatogastroenterology, 2009, 56 (90) :456-461.
  • 2中华医学会传染病与,寄生虫病学分会,肝病学分会.病毒性肝炎防治方案[J].中华肝脏病杂志,2000,8(6):324-329. 被引量:14010
  • 3Takahashi K, Umehara Y, Umehara M, et al. Plasma exchange- based plasma recycling dialysis system as an artificial liver sup- port[J]. Ther Apher Dial, 2008,12 (4) : 264-270.
  • 4Inoue K, Kourin A, Watanabe T, et al. Artificial liver support sys tern using large buffer volumes removes significant glutamine and is an ideal bridge to liver transplantation[J]. Transplant Proc, 2009,41(1) ;259-261.

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