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Kv1.3钾通道在Th17/Treg细胞诱导的自身免疫病中的作用

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摘要 钾离子在人体的多种生命活动中起着非常重要的作用,其功能的实现首先要通过细胞膜上的钾离子通道进入胞浆后与相应的位点结合或激活某些分子之后发挥一系列的生理生化效应。钾离子通道是镶嵌在脂质双分子层中可形成水性孔道的糖蛋白,是钾离子进出细胞的必经之路,对细胞功能的调节具有重要作用。钾离子通道广泛表达在多种细胞的表面,这些通道又根据细胞行驶的功能、细胞的兴奋性和膜电位的不同在细胞膜上有选择性的分布。
出处 《临床血液学杂志(输血与检验)》 CAS 2011年第3期370-372,374,共4页 Journal of Clinical Hematology(Blood Transfusion & Laboratory Medicine)
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