SO_3/γ-Al_2O_3固体酸催化合成环己酮乙二醇缩酮的工艺研究

Study on the synthesis process of cyclohexanone ethylene ketal catalyzed by SO_3/γ-Al_2O_3 solid acid

以环己酮和乙二醇为原料,SO3/γ-Al2O3固体酸为催化剂,环己烷为带水剂,通过醇酮亲核加成反应合成了环己酮乙二醇缩酮.较系统地研究了催化剂用量、酮醇摩尔比、反应时间等因素对产品收率的影响.实验结果表明:最佳工艺条件为n(环己酮)n(乙二醇)=1 1.4,催化剂0.5 g,环己烷10 mL,回流时间1.0 h,产物收率达87%以上,说明此SO3/γ-Al2O3固体酸具有良好的催化活性.

Cyclohexanone ethylene ketal was synthesized from cyclohexanone and ethylene by nucleophilic addition reaction,using SO3/γ-Al2O3 solid acid as the catalyst and cyclohexane as the water-carrying agent.The effects of varying the molar ratio of ketone and alcohol,catalyst dosage and reaction time on the yield were studied systematically.The experiment results showed that the optimal reaction conditions are as follows：the molar ratio of cyclohexanone to ethylene glycol is 1∶1.4,the amounts of catalyst and cyclohexane are 0.5g and 10mL respectively,and reflux reaction time is 1.0h.Under the conditions above,the yield of cyclohexanone ethylene ketal can reach 87%,which indicates the good catalytic activity of SO3/γ-Al2O3 solid acid.