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微小RNA在肿瘤侵袭转移中的作用

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摘要 微小RNA(miRNA)是一类长度为19-25个核苷酸对的非编码小分子RNA,通过与靶 mRNA互补配对而在转录水平上对基因的表达进行负调控.实验表明miRNA可通过调控其靶基因参与的信号通路,影响肿瘤的发生、发展和转移,发挥着类似原癌基因或抑癌基因的功能.因此研究miRNA在肿瘤侵袭转移调控中的作用有着重要意义.
机构地区 中国医科大学
出处 《医学信息》 2011年第12期4024-4025,共2页 Journal of Medical Information
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