摘要
目的比较红心鸭蛋与普通鸭蛋类胡萝卜素提取物对胃癌SGC-7901细胞增殖与凋亡的作用。方法采用噻唑蓝(MTT)法、流式细胞术、免疫组化法。结果红心鸭蛋类胡萝卜素提取物对SGC-7901细胞增殖抑制作用、凋亡诱导作用及上调促凋亡基因bcl-2、下调抑制凋亡基因Bax表达的作用显著强于普通鸭蛋类胡萝卜素提取物。结论红心鸭蛋类胡萝卜素提取物对SGC-7901细胞增殖抑制与凋亡诱导作用均显著强于普通红心鸭蛋类胡萝卜素提取物。
Objective To compare the effects of two kinds of carotenoids extracted from red yolk duck＇s eggs and the common duck＇s eggs on proliferation and apoptosis of human gastric carcinoma cell SGC-7901.Method MTT（methyl thiazolyl tetrazolium） assay,flow cytometry and immunohistochemistry method were used.Results Different concentrations of carotenoids in red yolk duck＇s eggs could remarkably inhibit the growth of SGC-7901 cells through modulating the expression of Bcl-2 and Bax,stronger than the carotenoids in the common duck＇s eggs.Conclusion The effect of carotenoids extracted from red yolk duck＇s eggs on proliferation and apoptosis of human gastric carcinoma SGC-7901 cell was much stronger than that from the common duck＇s eggs.
出处
《营养学报》
CAS
CSCD
北大核心
2011年第3期278-281,共4页
Acta Nutrimenta Sinica
