凝血过筛检测在深静脉血栓形成防治中的意义

Study on the Coagulation Change in Patients with Deep Venous Thrombosis

目的探讨深静脉血栓形成(DVT)患者凝血5项过筛试验的变化及其临床意义,以利于DVT的诊断及治疗监测。方法采用ACL TOP型全自动血凝分析仪测定aPTT、PT、TT、Fbg、INR。结果检测92例DVT患者凝血5项过筛试验均有不同程度的异常,其中检测的38例治疗前病例aPTT为26.6±2.93 s,Fbg含量为4.86±1.71 g/L,较之治愈组的54例aPTT 43.3±8.90 s、Fbg含量2.43±0.81 g/L,65例正常人组aPTT 29.8±2.92 s、Fbg含量3.21±0.68g/L组间差异有极显著意义。结论凝血5项过筛试验对DVT患者是否存在血栓前状态判断和抗血栓治疗的监测有重要临床意义。

Objective To investigate the coagulation change and its clinical significance in patients with deep venous thrombosis（DVT）.Methods The contents of aPTT,PT,TT,Fbg and INR were measured by American IL automatic analyzer（ACL TOP）.Results ACL TOP was used to detect the aPTT,PT,TT,Fbg and INR in 92 patients with deep venous thrombosis and the results of aPTT,PT,TT,Fbg,INR were significantly abnormality.The contents of aPTT 26.6±2.93 s and Fbg 4.86±1.71 g/L in group of 38 pretherapy group were significantly difference than those of curing and normal controls.Conclusion To investigate the coagulation change of patients with DVT and prethrombotic state（PTS） decision and antithromb therapy were con-sanguineously correlative to the high-frequency.