脂肪酶催化合成L-抗坏血酸有机酸酯的研究进展

Research progress of lipase-catalyzed synthesis of L-ascorbyl organic acid ester

为了拓宽L-抗坏血酸酯在维护人体健康中的应用,将L-抗坏血酸转化成L-抗坏血酸酯是经济可行的手段。综述了近年来酶催化L-抗坏血酸有机酸酯的研究进展,重点介绍了有机相中L-抗坏血酸饱和脂肪酸酯、不饱和脂肪酸酯、脂肪酸混合酯的酶促合成,对于酶的种类、有机溶剂的选择及分离纯化方法进行了探讨,并对酶催化L-抗坏血酸有机酸酯合成前景进行了展望。

To broaden the applications of L-ascorbic acid,it is an economical and feasible way to convert L-ascorbic acid into L-ascorbyl organic acid ester.The recent research progress of enzymatic synthesis of L-ascorbyl organic acid ester is summarized,by focusing on enzymatic synthesis of L-ascorbyl saturated fatty acid ester,unsaturated fatty acid ester and mixed fatty acid ester in organic solvents.The types of lipase,organic solvents and methods of separation and purification in the synthesis are discussed.Furthermore,the prospect of enzymatic synthesis of L-ascorbyl organic acid ester is also presented.