摘要
Direct aldol reactions of aldehydes and ketones can proceed smoothly in the presence of a catalytic amount of naphthol/sodium naphtholate(5 mol%) to afford the corresponding products with yields up to 98%.Such a bifunctional catalyst is more moderate than strong acid or base employed in direct aldol reactions.
Direct aldol reactions of aldehydes and ketones can proceed smoothly in the presence of a catalytic amount of naphthol/sodium naphtholate(5 mol%) to afford the corresponding products with yields up to 98%.Such a bifunctional catalyst is more moderate than strong acid or base employed in direct aldol reactions.
基金
supported by the Natural Science Foundation of China(Nos.20872120 and 20572087)
the Municipal Science Foundation of Chongqing City(No.2003-8118)
the Ministry of Education,PR of China(No.106141)
the Fundamental Research Funds for the Central Universities