摘要
A domino reaction of anilines with cyclic and acyclic enol ethers induced by catalytic amounts of TBPA^（·＋）（5 mol%） was investigated and a series of 2,4-disubstituted-1,2,3,4-tetrahydroquinolines were synthesized.Different from cyclic enol ethers, when acyclic enol ethers were used in the reaction,they serve as surrogates of acetaldehyde,producing a series of 2-methyl-4- anilino-1,2,3,4-tetrahydroquinolines.A single electron transfer mechanism was proposed to rationalize the products formation.
A domino reaction of anilines with cyclic and acyclic enol ethers induced by catalytic amounts of TBPA^（·＋）（5 mol%） was investigated and a series of 2,4-disubstituted-1,2,3,4-tetrahydroquinolines were synthesized.Different from cyclic enol ethers, when acyclic enol ethers were used in the reaction,they serve as surrogates of acetaldehyde,producing a series of 2-methyl-4- anilino-1,2,3,4-tetrahydroquinolines.A single electron transfer mechanism was proposed to rationalize the products formation.
基金
We thank NSFC(No.21002079)
Project(No.20096203120002)
supported by the Ministry of Education of the People's Republic of China.We also thank the third Knowledge and Technological Innovation Project(No.NWNUKJCXGC -03-75 and NWNU-KJCXGC-03-64) of Northwest Normal University for supporting our research
