小儿膀胱横纹肌肉瘤诊治分析

Diagnosis and treatment of bladder rhabdomyosarcoma in children： A report of 6 cases

目的探讨小儿膀胱横纹肌肉瘤的诊断及治疗方案。方法结合我院6例特征性病例的诊治方法，其中3例单纯行膀胱部分切除术，1例行膀胱部分切除＋化疗，1例行化疗＋膀胱部分切除＋放疗，1例行膀胱部分切除＋近距离照射治疗，并参考目前国内外文献报道，提出诊断及治疗意见。结果2例分别于接受治疗后12个月、14个月复发，另外4例随访2年无肿瘤复发。结论目前诊断小儿横纹肌肉瘤的主要手段是B超、CT检查，确诊需待术后病检。联合化疗、手术治疗、放射治疗是目前主要的治疗手段。

Objective To evaluate the diagnosis and treatment of bladder rhabdomyosarcoma in children. Methods Diagnosis and surgical programs were established in children with bladder rhabdomy- osarcoma from 6 typical cases admitted in our hospital in combination with literatures. Results Three patients were treated by partial cystectomy, one by partial cystectomy and chemotherapy, one by chemotherapy, partial eysteetomy and radiotherapy, and one by partial eystectomy and brachytherapy. Two patients relapsed 12 and 14 months after treatment respectively. The other four cases were alive without reoccurrence during the following two years. Conclusion The main methods to diagnose bladder rhabdomyosarcoma in children include ultrasound and CT. Pathological examination is used for exact diagnosis. Combination of chemotherapy, surgery and radiotherapy is the major treatment of bladder rhabdomyosarcoma. The 5 - year overall survival rate can reach 82%.