骶管注射脉络宁复合液治疗急性腰椎间盘突出症230例的临床研究

Clinical Research of Curative Effects of Sacral Canal Injection of Mailuoning for Acute Lumbar Intervertebral Disc in 230 Cases

目的:探讨骶管注射脉络宁复合液对急性腰椎间盘突出症的疗效。方法:将460例腰椎间盘突出症患者随机分为骶管注射组230例和常规对照组230例,疗程3～4w,治疗前及治疗后1d、1w和疗程结束后应用目测类比评分法(VAS)对疼痛进行评估,对症状、体征进行临床评定。结果:对照组和骶管注射组治疗前VAS评分分别为(8·6±1·4)和(8·8±1·4)分,对照组治疗后第1d及第1wVAS评分对照组分别为(8·2±0·6)和(5·3±0·9)分,骶管注射组分别为(5·5±0·9)和(2·7±1·1)分,2组止痛效果比较,差异有统计学意义(P<0·05)。结论:骶管注射脉络宁复合液对腰椎间盘突出症有较好的临床疗效。

Objective：To explore the efficacy of sacral canal injection of Mailuoning on acute lumbar intervertebral disc.Methods：The patients were randomized to the sacral canal injection group （n=230） and the traditional treatment group （n=230） for 3 to 4 weeks.The clinical symptoms and signs as well as the scores of VAS were assessed before treatment,on day1,week1 and the end of treatment.Results：At baseline the VAS score was （8.6±1.4） and （8.8±1.4）points in the traditional treatment group and the sacral canal injection group respectively,on day1 and Week1,it was （8.2±0.6）and（5.3±0.9）points of the traditional treatment group,and （5.5 ±0.9）and （2.7±1.1） of the sacral canal injection group respectively.There was significant difference in analgesic effects between the two groups （P0·05）.Conclusion：Sacral canal injection of Mailuoning is an effective treatment option for lumbar inrervertebral disc.