温肺平喘颗粒联合固本温肺贴膏治疗支气管哮喘30例疗效观察

Treatment of Bronchial Asthma by Wenfei Pingchuan Granule on top of Guben Wenfei Plaster

目的:观察温肺平喘颗粒联合固本温肺贴膏治疗支气管哮喘(中医分型为冷哮证)急性发作期的临床疗效。方法:将60例支气管哮喘急性发作期患者随机分为治疗组和对照组各30例,对照组采用吸入布地奈德吸入剂和茶碱缓释片治疗。治疗组采用温肺平喘颗粒联合固本温肺贴膏贴敷治疗,2组疗程均为10天。观察比较临床疗效、肺功能FEV1%、ACT评分和证候积分的变化。结果:治疗组总有效率为93·3%,对照组总有效率86·7%,2组治疗后疗效比较无显著性差异(P>0·05)。治疗后2组FEV1%和ACT评分与治疗前比较均明显升高,有显著性差异(P<0·05);治疗后2组FEV1%、ACT评分组间比较,无显著性差异(P>0·05)。治疗后2组哮喘证候积分明显降低,与治疗前比较,有显著性差异(P<0·05)。结论:温肺平喘颗粒联合固本温肺贴膏治疗支气管哮喘急性发作期临床疗效确切,并能改善肺功能。

Objective：To observe efficacy of Wenfei Pingchuan Granule on top of Guben Wenfei Plaster on acute onset of bronchial asthma （TCM pattern：cold wheezing）.Methods：Sixty patients with bronchial asthma were randomized to treatment group （n=30） and control group （n=30）.In the 10 day treatment phase,the control group took inhaled budesonide inhalation and theophylline sustainedrelease tablets.The treatment group was given Wenfei Pingchuan Granule and Guben Wenfei Plaster.Primary end point included clinical efficacy,lung function FEV1%,ACTscores,and syndromes scores.Results：Total effective rate of treatment group equaled 93.3%,total effective rate of control group was 86.7%,no significant difference （P0·05）.After treatment both groups increased significantly with FEV1%,ACTscores and syndromes scores （P0·05）,The post-treatment FEV1%,ACTscores were not significantly different between groups （P0·05）.Conclusion：Wenfei Pingchuan Granule on top of Guben Wenfei Plaster can treat acute onset of bronchial asthma and improve lung function.