摘要
目的:探讨地肤叶水提物对糖尿病小鼠的降糖作用。方法:通过标准化四氧嘧啶造模糖尿病小鼠。选取血糖相近的小鼠分3组进行实验,分别喂药10天、10天、7天后观察实验组降糖结果,进行统计分析;并对实验小鼠进行毒理学实验。结果:地肤叶水提物剂量在4·0g/kg灌胃给药,7～10日均有一定降糖作用,与对照组比较可下降20%左右,最高达34·5%。结论:地肤叶水提物具有一定降糖作用,且不具有明显的毒副作用。
Objective：To explore anti-diabetic effect of Difuye extract from water on diabetic mice model.Methods：Alloxan-induced diabetes mice with similar glucose values were selected,and given test extract for respectively 10 and 7 days,observed glucose values;carried out statistic analysis;and performed toxic experiment.Results：Anti-diabetic effect was shown after the extract was given 4.0g/kg intragastrically for 7-10 days,which was about 20% decrease,and 20% at most compared with glucose values of the control group.Conclusion：Difuye extract from water has definite anti-diabetic effect and no obvious side effects.
出处
《世界中医药》
CAS
2011年第3期258-259,共2页
World Chinese Medicine
基金
湖南省科学技术厅重大项目(2006SK2005)
