催化羟基化制备2,5-二甲基苯酚的研究

Research on the Preparation of 2,5-xylenol by Catalytic Hydroxylation

由2-萘酚经亚硝化、加成、络合、中和反应合成了C.I.颜料绿8(简称PG8).考察了对二甲苯/H2O2直接羟基化制备2,5-二甲基苯酚反应中PG8催化性能.结果表明该催化剂具有一定的催化活性.研究了催化剂用量、反应温度、反应时间、反应物摩尔比、溶剂等对催化剂活性的影响.20.0 mL乙腈溶剂,0.1 g催化剂,H2O2与对二甲苯摩尔比为5,温度60℃,反应5 h,对二甲苯的转化率达到55.9%,2,5-二甲基苯酚的收率达到10.1%.

After nitrosation,addition,complexing and neutrallization reaction of 2-naphthol,C.I.Pigment Green 8（PG8） was synthesized.Catalytic hydroxylation of p-xylene catalyzed by PG8 in the presence of H2O2 was studied.PG8 has catalytic activity for the hydroxylation of p-xylene.Effects of catalyst dosage,reaction temperature,reaction time,solvents,and mole ratio of H2O2 to p-xylene on the hydroxylation were determined.Under the conditions： 20.0 mL acetonitrile as the solvent,0.1 g PG8 as the catalyst,n（H2O2）∶n（p-xylene） = 5,reaction temperature 60 ℃,reaction time 5 h,conversion of p-xylene is 55.9% with a yield of 2,5-xylenol 10.1%.