摘要
目的研究大鼠肝大部切除后再生时贮脂细胞的动态变化。方法用结蛋白免疫组织化学法显示肝贮脂细胞并计量，以图像分析仪测灰度值。结果正常肝小叶内贮脂细胞呈网架状分布，肝大部切除后再生时贮脂细胞数量递减，至第５ｄ时为正常肝的１／３。结论肝大部切除后再生时贮脂细胞动态变化明显不同于肝中毒等损伤后的增殖变化。
Objective\ To study the kinetic change of hepatic fat storing cells (FSC) in the regenerative process after subtotal hepatectomy of rats. Methods\ The hepatic FSC were showed and measured by means of desmin immunohistochemical method. Grey degree numerical value was measured with image analyser. Results\ The rat FSC were extensively distributed in liver lobules and constituted the supporting network. Within 5 days after hepatectomy, the number of desmin positive FSC was decreased toward to 1/3 of that in normal liver. Conclusion\ The kinetics of FSC in regenerating liver after hepatectomy is different from reproduction kinetic of the liver poisoning or injure.
出处
《解剖学报》
CAS
CSCD
北大核心
1999年第3期282-283,I019,共3页
Acta Anatomica Sinica
关键词
肝贮脂细胞
结蛋白
肝大部切除
肝再生
Hepatic fat storing cell
Desmin
Subtotal hepatectomy
Immunohistochemistry
