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CHEK2基因与乳腺癌的关系

CHEK2 gene and breast cancer
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摘要 CHEK2是一个重要的乳腺癌易感基因。同时，CHEK2基因突变与乳腺癌患者的病理特征及预后有一定关系。对CHEK2基因突变的检测可能对乳腺癌的治疗具有一定的指导作用。但CHEK2基因突变在中国人群中的作用尚待进一步研究。 CHEK2 is an important susceptibility gene of breast cancer. CHEK2 gene mutations are related to pathologic features and prognosis of breast cancer. So the test of CHEK2 gene mutations may be has certain indication role in the treatment of breast cancer. However, the role of CHEK2 gene mutations in Chinese population still needs further research.
作者 廖绍光 王雅杰
机构地区 上海第二军医大学附属长海医院肿瘤科
出处 《国际肿瘤学杂志》 CAS 2011年第6期447-449,共3页 Journal of International Oncology
关键词 基因 突变 乳腺肿瘤 CHEK2 Gene Mutation Breast neoplasms CHEK2
分类号 R737.9 [医药卫生—肿瘤]
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参考文献30

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二级参考文献12

  • 1宋传贵,胡震,袁文涛,狄根红,沈镇宙,黄薇,邵志敏.中国上海家族性乳腺癌BRCA1和BRCA2基因的突变[J].中华医学遗传学杂志,2006,23(1):27-31. 被引量：29
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国际肿瘤学杂志
2011年 第6期

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