喉罩对腹腔镜胆囊切除术全麻患者应激反应的影响

Effect of LMA on cardiovascular stress response during general anesthesia in patients under going laparoscopy cholecystectomy

目的评价全麻喉罩通气对患者应激反应的影响。方法选择40例全麻腹腔镜胆囊切除术患者随机均分为全麻喉罩组(Ⅰ组)和气管插管组(Ⅱ组)。监测BP、HR、ECG、SpO_2、PETCO_2,并于诱导前(T_0)和诱导后3 min(T_1)、6 min(T_2)、10 min(T_3)抽血查血浆皮质醇的浓度。结果Ⅱ组T_1、T_2时的HR、MAP及血浆皮质醇水平明显高于T_0时和Ⅰ组(P<0.05)。结论全麻喉罩通气用于腹腔镜胆囊切除术患者,应激反应明显轻于气管插管。

Objective To investigate the effect of LMA ventilation on stress response during general anesthesia in the patients undergoing laparoscopy cholecystectomy （LC）. Methods Forty LC patients were randomly divided into two groups with 20 cases each. Ventilation was performed with LMA （ group Ⅰ ） or tracheal intubation （ group Ⅱ ）. The BP, HR, SpO2 , PETCO2 and ECG were recorded. The levels of plasma cortisol （ COR ） were detected before （ TO ）, at 3 min （ T1 ）, 6 rain （T2 ）, and 10 rain（ T3 ） after anesthesia induction. Results The levels of COR, BP and HR at T1 and T2 in group Ⅰ were higher than those at To and in group Ⅱ （ P 〈 0. 05 ）. Conclusion Compared to conventional tracheal intubation, the stress response is lower during ventilation with LMA in LC patients under general anesthesia.