子宫内膜异位症术后孕三烯酮治疗临床分析

目的观察子宫内膜异位症术后应用孕三烯酮的临床效果,提高治疗水平。方法选取自2006年3月～2010年8月收治的138例子宫内膜异位症手术患者随机分为观察组(术后孕三烯酮治疗组)和对照组(术后无用药组)各69例,比较两组患者的治疗效果。结果观察组痊愈50例,有效17例,复发2例,总有效率为97.1%,复发率为2.9%;对照组痊愈43例,有效18例,复发8例,总有效率为11.6%;对照组患者治疗前后激素水平均无明显变化,但观察组E2、P治疗前后有明显改变,且与对照组治疗后水平比较差异显著(P<0.01);观察组在服药过程中不良反应发生率为14.5%。结论子宫内膜异位症术后应用孕三烯酮可以降低术后复发率,但应注意不良反应问题。

Objective To observe the application of endometriosis after the clinical effects of gestrinone,improve the therapeutic level. Methods In our hospital from March 2007 to August 2009 admitted 138 cases of uterine endometriosis surgery were randomly divided into two groups（postoperative gestrinone treatment group） and control group（no treatment after surgery group） of the 69 cases,patient outcomes were compared. Results 50 patients were cured,effective in 17 cases,recurrence occurred in 2 cases,the total effective rate was 97.1%,the recurrence rate was 2.9%;control group,43 patients cured,effective in 18 cases,8 cases of recurrence,the total effective rate was 11.6%;the control group before and after treatment in patients with no significant change in hormone levels,but the observation group E2,P changed significantly before and after treatment,and the level of the control group after treatment were significant differences（P〈0.01）;observation group taking the drug adverse reaction rate during the 14.5%. Conclusion Postoperative endometriosis gestrinone reduce the recurrence rate,but the problem of adverse reactions should be noted.