14例涎腺基底细胞腺癌的临床病理分析

Basal cell adenocarcinoma of the salivary gland:a clinicopathologic study of 14 cases

目的 总结涎腺基底细胞腺癌的临床及病理特点、生物学行为及治疗效果。方法 对14例涎腺基底细胞腺癌患者进行临床病理分析。结果 其临床特点为 :女性多于男性 ,发病部位以小涎腺为常见 ,颈淋巴结转移率为 2 1 4% ,远处转移率为 14 3% ,患者预后相对较差。组织病理表现类似于基底细胞腺瘤 ,但有较多核分裂象和浸润性生长的特点。结论 其生物学行为属中度恶性肿瘤 ,治疗以根治性切除为主 ,病变广泛者可考虑选择性颈淋巴清扫术。

Objective To study clinicopathologic features and behaviour of the basal cell adenocarcinoma of salivary gland tumor and prognosis of the patients, Methods 14 cases with basal cell adenocarcinoma were studied clinicopathologically Results The clinical features were as follows: females more than males; most frequently in the minor salivary glands; 21 4% of cervical lymph node metastasis and 14 3% of distant metastasis; and rather poor prognosis The histopathologic appearances were similar to those of basal cell adenoma, but with more mitotic figures and infiltrating growth.Conclusion This tumor was of moderate grade malignancy. It must be treated radically The elective neck dissection could be considered for the patients with extensive tumors