阿托伐他汀治疗慢性肾功能不全30例临床分析

The clinical analysis of atorvastatin therapy for chronic renal insufficiency in 30 cases

目的对阿托伐他汀治疗慢性肾功能不全进行临床分析。方法将58例慢性肾功能不全患者随机分为治疗组(30例)和对照组(28例)。两组患者均予以常规西医治疗,治疗组在常规治疗的基础上再加用阿托伐他汀20 mg/d。结果本组病例就诊后24 h内即明确诊断者56例(96.55%),就诊后2～4 d内明确诊断者2例(3.45%)。两组治疗4周后24 h尿蛋白定量比较,治疗组疗效优于对照组,差异有统计学意义(P<0.05)。治疗组总有效率28例(93.33%)优于对照组,差异有统计学意义(P<0.05)。结论在西医治疗慢性肾脏病的基础上加用阿托伐他汀治疗,疗效好。

Objective Atorvastatin for treatment of chronic renal insufficiency clinical analysis. Methods 58 eases of chronic renal insufficiency patients were randomly divided into the treatment group （30 eases） and the control group （28 cases） two groups of patients are Compared to conventional treatment group of western medicine therapy, based on routine treatment and then add a atorvastatin 20 mg/d. Results After treatment the group of cases is diagnosed within 24 h, 56 patients （96. 55% ）, treatment within 2 -4 d after the diagnosis in 2 cases （3.45%）. Two groups of four weeks after treatment for 24 h urine protein quantitative comparison, the curative effect of treatment group was better than control group, the difference was statistically significant （ P 〈 0. 05 ） treatment group total effectiveness 28 patients （93.33 % ） than control group, the difference was statistically significant （ P 〈 0. 05 ）. Conclusion In western medicine therapy on the ＇basis of chronic kidney disease combined with atorvastatin treatment, has good curative effect.