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苯磺酸氨氯地平联合厄贝沙坦治疗中重度高血压的疗效观察 被引量:3

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摘要 目的观察苯磺酸氨氯地平联合厄贝沙坦治疗中重度高血压的临床疗效。方法选择中重度高血压患者120例,随机分为A组(口服苯磺酸氨氯地平5mg,加厄贝沙坦150mg,1次/d)、B组(口服苯磺酸氨氯地平5mg,1次/d),2个月时测血压进行疗效分析。结果两组血压均有下降,A组有效率93.3%,B组有效率66.7%,两组比较,差异有统计学意义(P<0.05)。结论苯磺酸氨氯地平联合厄贝沙坦较单用苯磺酸氨氯地平治疗更有效,两药联用,能发挥协同作用,提高降压疗效。
出处 《中外医学研究》 2011年第18期29-29,共1页 CHINESE AND FOREIGN MEDICAL RESEARCH
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  • 1刘力生.2004年中国高血压防治指南(实用本)[J].中华心血管病杂志,2004,32(12):1060-1064. 被引量:2620
  • 2Silvestre JS,Tamarat R,Senbonmatsu T,et al.Antiangiogenic effect of angiotensin Ⅱ type 2 receptor in ischemia-induced angiogenesis in mice hindlimb[J].Citc Res,2002,90(10):1072-1079.
  • 3Gallinat S,Busche S,Schutze S,et al.AT2 receptor stimulation induces generation of ceramides in PC21W cells[J].FEBS Lett,1999,443(1):75-79.
  • 4Jalowy A,Schulz R,Dorge H,et al.Infarct size reduction by AT1-receptor blockade through a signal cascade of AT2-receptor activation,bradykinin and prostaglandins in pigs[J].J Am Coll Cardiol,1998,32(6):1787-1796.
  • 5Yang Z,Bove CM,French BA,et al.Angiotensin Ⅱ type 2 receptor overexpression preserves left ventricular function after myocardial infarction[J].Circulation,2002,106(1):106-111.
  • 6Adachi Y,Saito Y,Kishimoto I,et al.Angiotensin Ⅱ type 2 receptor deficiency exacerbates heart failure and reduces survival after acute myocardial infarction in mice[J].Circulation,2003,107(19):2406-2408.
  • 7Wang LX,Ideishi M,Yahiro E,et al.Mechanism of the cardioprotective effect of inhibition of the renin-angiotensin system on ischemia/reperfusion-induced myocardial injury[J].Hypertens Res,2001,24 (2):179-187.
  • 8de Gasparo M,Catt KJ,Inagami T,et al.International union of pharmacology.ⅩⅩⅢ.The angiotensin Ⅱ receptors[J].Pharmacol Rev,2000,52(3):415-472.
  • 9Stoll M,Unger T.Angiotensin and its AT2 receptor:new insights into an old system[J].Regul Pept,2001,99(2-3):175-182.
  • 10Utsunomiya H,Nakamura M,Kakudo K,et al.Angiotensin Ⅱ AT2 receptor localization in cardiovascular tissues by its antibody developed in AT2 gene-deleted mice[J].Regul Pept,2005,126 (3):155-161.

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