体外循环术后发生全身性炎症反应综合征的相关危险因素分析

Risk factors for the development of SIRS in patients after cardiopulmonary bypass

目的探讨体外循环心脏术后发生全身性炎症反应综合征（SIRS）可能的危险因素。方法择期行体外循环心脏术后患者83例，年龄6个月至66岁，NYHAI或Ⅱ级，体重7～97kg。术后24h内进行SIRS评分，根据SIRS评分，分为2组，SIRS组（S组，SIRS评分92分）和非SIRS组（u组，SIRS评分〈2分）。用logistic回归分析，筛选SIRS发生的危险因素。结果SIRS发生率为83．13％，体外循环术后发生SIRS的危险因素与动脉血氧分压（PaO：），滞留ICU时间以及术后心率有关（OR=0．518，g．334，3．607，P〈0．05）。结论动脉血氧分压（PaO：），滞留ICU时间及心率是体外循环术后发生SIRS可能的危险因素。

Objective To determine the risk factors for the development of systemic inflammatory response syndrome （SIRS） in the patients after cardiopulmonary bypass has been constructed. Methods Eighty three NYHA Ⅰ or Ⅱ patients, aged 6month-66yr, weighting 7 -97 kg, undergoing cardiopulmonary bypass, were enrolled in this study. SIRS score was performed during 24 h after the surgery. The patients were divided into 2 groups： SIRS group（S, SIRS seore≥2） and non-SIRS group（U, SIRS score 〈2）. The risk factors were identified by logistic regression analysis. Results The incidence of SIRS was 83. 13% . Logistic analysis indicated that arterial oxygen pressure （ PaO2 ） , retention time, and postoperative heart rate were closely related with the development of SIRS in patients on ICU after cardiopulmonary bypass （ OR = 0.518,4.334,3.607, P 〈0.05）. Conclusions The arterial oxygen pressure （PaO2）, ICU stay, and heart rate after eardiopulmonary bypass has been constructed can be served as the risk factors for the development of SIRS in patients.