超声内镜下胃间质瘤特征与病理诊断相关性研究

Features endoscopic ultrasonography and pathology of gastric stromal tumors

目的通过分析不同侵袭危险性的胃间质瘤的内镜超声特征，探讨内镜超声检查在胃间质瘤诊治中的价值。方法回顾性分析34例胃间质瘤患者的临床资料，按照Fletcher推荐的胃肠间质瘤生物学行为评价标准进行分组，将其内镜超声特点进行归纳，进行统计学分析。结果胃间质瘤最大径平均为6.7cm。侵袭危险性高的组其回声不均、肿瘤巨大、外形不规则、溃疡形成特点常见，组间差异有统计学意义（P〈0．05）。结论根据内镜超声表现中大小、形态、回声、有无溃疡4个特征对胃间质瘤进行治疗前综合评价，有利于指导胃间质瘤的进一步治疗。

Objective To evaluate endoscopic ultrasonography （EUS） for diagnosis of gastric stroreal tumors （GST） by analyzing EUS features of tumors with different invasive capacities. Methods Clinical data of 34 patients with GST were analyzed retrospectively. The tumors were classified according to Fletcher＇s GIST biological behavior ranking system and the corresponding EUS features were analyzed. Resuits The mean maximal diameter of GST in this cohort was 6.7cm. The echo heterogeneity, big tumors size, irregular shape and ulceration were more common in tumors of high risk （P 〈 0. 05）. Conclusion Tumor size, shape, echo quality and ulceration detected by EUS are useful features for pretreatment evaluation of GST, and can guide the choice of following managements.