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CD4＾＋CD25＾＋调节性T细胞在艾滋病病毒感染中的作用

Role of CD4^＋CD25^＋ regulatory T cells in human immunodeficieacy virus infection
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摘要 CD4＾＋CD25＾＋调节性T细胞（Tregs）是一类具有特殊免疫调节功能的T细胞亚群，是Tregs的重要组成部分，参与多种感染性疾病的免疫应答，在病毒感染的慢性化、免疫病理、阻止自身免疫应答和维持机体免疫平衡等方面发挥重要的作用。此文就（CD4＾＋CD25＾＋ Tregs在HIV感染进程中的作用作了综述。 CD4^＋CD25^＋ regulatory T cells （Tregs） is a group of T lymphocyte subsets possessing specific functions in immunological regulation and appear to be critical components of Tregs, which participate in the immune response to multiple infectious diseases. CD4^＋CD25^＋ Tregs play significant roles in the chronicity of vires infection, immunopathogenesis, prevention of autoimmune response and maintenance for the immunologic balance. The role of CD4^＋CD25^＋ Tregs in the disease progression of HIV infection is reviewed in this article.
作者 刘金峰 李凌华 唐小平
机构地区 广州医学院附属市八人民医院传染病研究所
出处 《国际流行病学传染病学杂志》 CAS 2011年第3期179-182,共4页 International Journal of Epidemiology and Infectious Disease
关键词 T淋巴细胞 调节性 HIV 免疫抑制 T lymphocytes, regulatory HIV lmmunosuppression
分类号 R512.91 [医药卫生—内科学]
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参考文献20

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二级参考文献15

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国际流行病学传染病学杂志
2011年 第3期

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