摘要
Aremarkable advance in sperm physiology has recently been published in Nature. Two groups using patch damping techniques on human sperm have solved a mystery about the sperm cell that has puzzled both andrologists and those involved in non-genomic cellular signalling for over 20 years. In these papers, Lishko1 and Strunker2 independently demonstrate that the universal characteristic effect of progesterone on sperm--a rapid influx of calcium--is via a sperm-specific channel CatSper.
Aremarkable advance in sperm physiology has recently been published in Nature. Two groups using patch damping techniques on human sperm have solved a mystery about the sperm cell that has puzzled both andrologists and those involved in non-genomic cellular signalling for over 20 years. In these papers, Lishko1 and Strunker2 independently demonstrate that the universal characteristic effect of progesterone on sperm--a rapid influx of calcium--is via a sperm-specific channel CatSper.