微波辐射下2-硝基芴与芳香醛的Knoevenagel反应

Microwave-Assisted Knoevenagel Reaction of 2-Nitrofluorene with Aromatic Aldehyde

以2-硝基芴和芳香醛为原料,在碱性条件下,微波辐射(500 W)反应5～8 min,非常方便地合成了系列未见文献报道的Knoevenagel反应产物,该方法操作简单、产率较高(78%～89%).其结构经IR,1H NMR,MS和元素分析进行了表征.对化合物3a～3d进行了紫外吸收和荧光测定,结果显示这些化合物具有荧光特性.

A series of novel Knoevenagel products of 2-nitrofluorene to a series of aromatic aldehydes were obtained in the presence of sodium hydroxide under microwave irradiation（500 W） within short reaction times（5-8 min） in high yields（78%-89%）.The structures of the products were characterized by IR,1H NMR,MS techniques and elemental analysis.The UV absorption and fluorescent spectra of compounds 3a-3d were detected and showed that they had fluorescence.