重度阻塞性睡眠呼吸暂停征的持续正压通气治疗分析

Analysis of treatment of continuous positive airway pressure on the severe obstructive sleep apnea hypopnea syndrome

[目的]探讨分析持续正压通气治疗对重度阻塞性睡眠呼吸暂停征(OSAHS)的疗效。[方法]选择经多导睡眠监测检查为重度OSAHS患者且行智能型经鼻正压通气(AUTO SET)治疗3个月的45例患者为对象。对呼吸暂停低通气指数(apneahyponeaindex,AHI)、最低/平均血氧饱和度(LSaO2/MSaO2)、平均血压等指标进行观察。[结果]治疗后患者打鼾、呼吸暂停和白天嗜睡等症状明显改善。AHI:(10.36±2.27)次/h,LSaO2:(85.91±5.37)%;MSaO2:(92.87±5.56)%,平均血压24 h SBP:(135.69±8.31)mmHg,24 h DBP:(87.42±6.65)mmHg。与治疗前AHI:(61.23±5.38)次/h,LSaO2:(42.45±5.78)%,MSaO2:(75.12±5.68)%,24 h SBP:(165.21±7.97)mmHg,24 h DBP(105.62±5.43)mmHg相比均有明显变化,差异具有显著性意义(P<0.05)。[结论]重度阻塞性睡眠呼吸暂停征经过AUTO SET治疗可缓解患者临床症状及改善睡眠指标。

[Objective] To investigate the effects of continuous positive airway pressure（CPAP） on severe OSAHS.[Methods] Forty-five severe OSAHS cases checked by polysomnography and treated by intelligent nasal continuous positive airway pressure（AUTO SET） for 1 year were selected for this study.All patients′ apnea hyponea index（AHI）,lowest and average oxygen saturation（LSaO2/MSaO2）,and blood pressure were measured.[Results] After treatment,the apnea index AHI：（10.36±2.27）/h,LSaO2：（85.91±5.37）%,MSaO2：（92.87±5.56）%,mean blood pressure 24 h SBP：（135.69±8.31）mmHg;24 h DBP：（87.42±6.65）mmHg showed significantly change（P0.05） if compared to pre-treatment data AHI：（61.23±5.38）/h;LSaO2：（42.45±5.78）%,MSaO2：（75.12±5.68）%,24 h SBP：（165.21±7.97）mmHg,24 h DBP：（105.62±5.43）mmHg.[Conclusion] Severe symptoms of obstructive sleep apnea can be improved if it is treated by AUTO SET.