艾滋病合并机会性感染38例临床分析

Clinical analysis of 38 AIDS patients with opportunistic infections

目的:了解在我科治疗的38例艾滋病患者机会性感染的疾病谱,临床数据的特点,高效抗反转录病毒治疗与病人转归的关系。方法:采用回顾性分析的方法对在我科治疗的艾滋病合并机会性感染38例相关信息进行分析。结果:死亡16例,病死率42.11%。结论:艾滋病合并机会性感染病原多样,且可侵犯全身多个系统。机会性感染是艾滋病病人就诊和死亡的主要原因。高效抗反转录病毒治疗可以使艾滋病病人免疫系统得到部分重建,减少机会性感染的发生,延长艾滋病病人的生命。

Objective：To find out the spectrums of the 38 AIDS patient associated with opportunistic infections undergone treatment in our department and characteristics of the clinical profiles as well as the relationship between the outcomes and highly active antiretroviral therapy（ HAART）. Methods：The clinical information was retrospectively analyzed in the 38 HIV-infeeted patients associated with opportunistic infections. Results： There were 16 deaths of the 38 patients （42. 1 1% ）. Conclusion ： AIDS with opportunistic infections varied a lot in pathogenesis and could affect several body systems. Commonly, opportunistic infections drove the patients to seek medical advice and the infections should be responsible for the death from AIDS. HAART may effectively aid the patients in restoration of their immune systems, reducing the opportunistic infections and delay the survival of these patients.