利妥昔单抗联合CHOP治疗非霍奇金淋巴瘤的现状(文献综述)
摘要
非霍奇金淋巴瘤(non-Hodgkin's lymphoma,NHL)是目前发病率增长速度最快的恶性肿瘤,有90%以上淋巴瘤为NHL。传统的治疗方法以长春新碱、环磷酰胺、泼尼松、阿霉素(CHOP)方案为主。RTX(rituximab,RTX)是特异性针对B淋巴细胞(CD20)的人鼠嵌合单克隆抗体,在1997年获美国食品和药品管理局(FDA)批准用于治疗人类恶性、
出处
《放射免疫学杂志》
CAS
2011年第3期276-278,共3页
Journal of Radioimmanology
参考文献19
-
1Torres-Garcla E, Ferro-Flores G, Arteaga de Murphy C, et al. Bioki- hellos and dosimetry of 188Re-anti-CD20 in patients with non-Hodgkin' s lymphoma: prelimitmry experience [ J ]. Arch Med Res, 2008,39 ( 1 ) : 100-109.
-
2Jacobs SA, Foon KA. The expanding role of rituxdmab and radioim- munotherapy in the treatment of B-cell lymphomas[ J ]. Expert Opin Biol Ther, 2007,7 ( 11 ) : 1749-1762,.
-
3Macardle PJ, Nicholson IC. CD20 [ J ]. J Biol Regul Homeost A- gents, 2002,16(2) :136-138.
-
4Huhln LE, Hausner MA, Huhin PM, et al. CIY20 (pan-B cell) an- tigen is expressed at a low level on a subpopulation of human T lympho- cytes[J]. Cytometry,1993,14(2) :196-204.
-
5Coiffier B. Rituximab therapy in malignant 1 ymphoma[ J ]. Oneo- gene, 2007, 26(25) :3603-3613.
-
6Glennie MJ, French RR, Cragg MS, et al. Mechanisms of killing by anti-C1)20 monclonal antibodies[ J]. Mol Immunol, 2007,44(16) :3823- 3837.
-
7Mounier N, Bfiere J, Gisselbrecht C, et al. Rituxlmab plus CHOP (R-CHOP) overcomes Bcl-2-associated resistance to chemotherapy in eld- erly patients with diffuse large B-cell lymphoma (DLBCL) [J]. Blood, 2003,101 ( 11 ) :42794284.
-
8McLaulhlin P, Hagemeister FB, Grillo-Ltipez M. Rituximab in indo- lent lymphoma : the single-agent pivotal trial[ J ]. Semin Oncol, 1999,26 (5 Suppl 14) :79-87.
-
9Shaw T, Quan J, Totoritis MC. 8 cell therapy for rheumatoid arthri- tis: the ritmdmab (anfi-CD20) experience[J]. Ann Rheum Dis, 2003,62(Suppl 2) : ii55-ii59.
-
10Sehn LH, Donaldson J, Chhanabhai M, ctal. Introduction oir corn- bined CHOP plus rituximab therapy dramatically improved outcome of dif-fuse large BceLl lymphoma in British ColumbiaC[J]. J Clin Oucol, 2005, 23(22) :5027-5033.
二级参考文献56
-
1Pfreundschuh M, Trumper L, Osterborg A, et al. CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomized controlled trial by the MabThera International Trial (MINT) Group[J]. Lancet Oncol, 2006, 7(5): 379- 391.
-
2Feugier P, Van Hoof A, Sebban C, et al. Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: a study by the Groupe d'Etude des Lymphomes de I'Adulte[J]. J Clin Oncol, 2005, 23(18): 4117-4126.
-
3Coiffier B, Feugier P, Mounier N, et al. Long-term results of the GELA study comparing R-CHOP and CHOP chemotherapy in older patients with diffuse large B-cell lymphoma show good survival in poor-risk patients[Meeting Abstracts][J]. J Clin Oncol, 2007, 25 (18S): 8009.
-
4Pfreundschuh M, Schubert J, Ziepert M, et al. Six versus eight cycles of bi-weekly CHOP-14 with or without rituximab in elderly patients with aggressive CD 10 B-cell lymphomas: a randomized controlled trial (RICOVER-60)[J]. Lancet Oncol, 2008, 9(2): 105- 116.
-
5Lenz G, Dreyling M, Hoster E, et al. Immunochemotherapy with rituximab and eyelophosphamide, doxorubicin, vineristine, and prednisoue significantly improves response and time to treatment failure, but not long-term outcome in patients with previouslyuntreated mantle cell lymphoma: results of a prospective randomized trial of the German Low Grade Lymphoma Study Group (GLSG)[J]. J Clin Oncol, 2005, 23(9):1984-1992.
-
6Hainsworth JD, Litchy S, Burris HA 3rd, et al. Rituximab as firstline and maintenance therapy for patients with indolent non-Hodgkin's lymphoma[J]. J Clin Oncol, 2002, 20(20): 4261-4267.
-
7Ghiehnini M, Schmitz SF, Cogliatti SB, et al. Prolonged treatment with rituximab in patients with follicular lymphoma significantly increases event-free survival and response duration compared with the standard weekly×4 schedule[J]. Blood, 2004, 103(12): 4416- 4423.
-
8Gordan LN, Grow WB, Pusateri A, et al. Phase II trial of individualized rituximab dosing for patients with CD20-positive lymphoproliferative disorders[J]. J Clin Oncol, 2005, 23(6): 1096- 1102.
-
9Hagenbeek A, Van Glabbeke M, Teodorovic I, et al. The role of rituximab maintenance treatment in relapsed follicular NHL: in interim analysis of the EORTC randomized intergroup trial[Meeting Abstracts]. Ann Oncol, 2005, 16: v52. Abstract 61.
-
10Morrison VA, Weller EA, Habermann TM, et al. Maintenance rituximab (MR) compared to observation (OBS) after R-CHOP or CHOP in older patients (pts) with diffuse large B-cell lymphoma (DLBCL): an Intergroup E4494/C9793 update[Meeting Abstracts]. J Clin Oncol. 2007, 25(18S): 8011.
共引文献36
-
1沈刚,沈文香.20例美罗华联合CHOP方案治疗非霍奇金淋巴瘤临床疗效及不良反应观察[J].中国继续医学教育,2013,5(3):34-35. 被引量:1
-
2陈倩超,刘韬,黄红兵.3种用药频次较高的抗肿瘤靶向药物临床使用调研[J].今日药学,2009,19(9):44-47. 被引量:3
-
3陈倩超,刘韬,李志铭,潘莹,黄红兵.3种新型抗肿瘤靶向抗体药物的临床应用状况评价[J].中国新药杂志,2009,18(18):1798-1802. 被引量:4
-
4冯兰英,俞建平.弥漫性大B细胞淋巴瘤经利妥昔单抗联合化疗后进展伴CD_(20)抗原表达丢失1例报道并文献复习[J].实用肿瘤杂志,2010,25(2):188-190. 被引量:3
-
5宋春鸽,画宝勇.美罗华治疗B细胞性非霍奇金淋巴瘤临床观察[J].医药论坛杂志,2010,31(9):62-63. 被引量:1
-
6冯艺,周宇红.利妥昔单抗联合CHOP化疗方案治疗B细胞非霍奇金淋巴瘤感染病例观察[J].中国临床医学,2010,17(6):889-891. 被引量:11
-
7杨绍灵,苏鹏,施玲玲.利妥昔单抗联合CHOP与单用CHOP方案治疗初治弥漫大B细胞型淋巴瘤的对比研究[J].现代肿瘤医学,2011,19(10):2069-2071. 被引量:13
-
8高珊(综述),克晓燕(审校).滤泡性淋巴瘤新药研究进展[J].白血病.淋巴瘤,2011,20(12):762-765.
-
9闫秀云.利妥昔单抗联合CHOP方案治疗非霍奇金淋巴瘤临床研究[J].中国医刊,2012,47(3):64-65. 被引量:9
-
10刘默,杨清明,彭朝津,刘芳,杜瑜,周宏伟.利妥昔单抗联合化疗治疗弥漫大B细胞性淋巴瘤疗效分析[J].中国误诊学杂志,2012,12(2):338-339. 被引量:2
-
1陈琳,应明真,王雅杰.利妥昔单抗治疗血液系统恶性肿瘤相关进展[J].医学研究杂志,2013,42(3):170-173. 被引量:5
-
2王仁生,徐寒子,黄光武,韦波.西妥昔单抗联合放射及加热诱导鼻咽癌细胞系凋亡的实验研究[J].中华放射肿瘤学杂志,2009,18(4):289-290. 被引量:1
-
3罗聪,应杰儿.贝伐单抗在结直肠癌靶向治疗中的研究进展[J].中国全科医学,2011,14(29):3407-3409. 被引量:8
-
4何裕民.“带癌生存”不是梦[J].家庭用药,2006(10):61-61.
-
5陈三妹.恶性肿瘤患者应用^(131)I肿瘤细胞核人鼠嵌合单克隆抗体的护理体会[J].山西医药杂志(上半月),2008,37(9):861-862. 被引量:1
-
6王丽峰,迟小华,刘向健.蛋白酶体抑制剂治疗多发性骨髓瘤[J].白血病.淋巴瘤,2006,15(6):478-480. 被引量:5
-
7浦权.进一步提高慢性髓细胞白血病的治疗水平[J].中国健康月刊,2007(4):42-43.
-
8浦权.进一步提高慢性髓细胞白血病的治疗水平[J].中华内科杂志,2006,45(5):353-354. 被引量:2
-
9张建军,王静.转移性肾癌的分子靶向治疗进展[J].实用医学杂志,2014,30(11):1685-1687. 被引量:4
-
10罗云,娄世锋,陈姝.小剂量利妥昔单抗治疗初发的系统性红斑狼疮[J].重庆医学,2009,38(21):2775-2776. 被引量:1