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硼替佐米致多发性骨髓瘤患者急性肺损伤一例 被引量：6

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摘要 患者男性,69岁.2010年1月入院,诊断为多发性骨髓瘤Ⅲ期A组,IgAλ型.体检：贫血貌;双肺触觉语颤正常对称,听诊闻及呼吸音稍低,未闻及干湿哕音及胸膜摩擦音;余未见异常.予患者PD方案化疗[硼替佐米2.7 mg（1.3mg/m2）第1、4、8、11天,地塞米松40 mg第1、4、8、11天].患者IgA由104.0 g/L降至30.6 g/L,考虑化疗有效.化疗第3天患者出现发热,
作者 闫涵 欧晋平 章巍 岑溪南 任汉云
机构地区 北京大学第一医院血液内科 北京大学第一医院呼吸内科
出处 《中华内科杂志》 CAS CSCD 北大核心 2011年第6期517-518,共2页 Chinese Journal of Internal Medicine
关键词 多发性骨髓瘤 硼替佐米 急性肺损伤 患者 触觉语颤 PD方案 地塞米松 IGA
分类号 R733.3 [医药卫生—肿瘤]
  • 相关文献

参考文献9

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同被引文献46

  • 1王亚非,邱录贵,邹德慧,王迎,邓书会,李园,徐燕,钱林生,赵耀中.硼替佐米治疗多发性骨髓瘤后严重肺损伤二例报告并文献复习[J].白血病．淋巴瘤,2008,17(2). 被引量：12
  • 2侯健,周帆,张永贞,景燕.硼替佐米治疗复发、难治性多发性骨髓瘤[J].中国新药与临床杂志,2005,24(7):579-581. 被引量：13
  • 3急性肺损伤/急性呼吸窘迫综合征诊断和治疗指南(2006)[J].中国实用外科杂志,2007,27(1):1-6. 被引量：198
  • 4Voortman J, Giaccone G. Severe reversible cardiac failure after bortezomib treatment combined with chemotherapy in a non-small cell lung cancer patient: a case report. BMC Cancer, 2006, 6:129.
  • 5Boyer JE, Batra RB, Ascensao JL, et al. Severe pulmonary complication after bortezomib treatment for multiple myeloma. Blood, 2006,108 : 1113.
  • 6Gotoh A, Ohyashiki K, Oshimi K,et al. Lung injury associated with bortezomib therapy in relapsed/refractory multiple myeloma in Japan: a questionnaire-based report from the "lung injury by bortezomib" joint committee of the Japanese society of hematology and the Japanese society of clinical hemalology. IntJ Hematol,2006, 84:406-412.
  • 7Pitini V, A1Tigo C, Ahavilla G, et al. Severe pulmonary complications after bortezomib treatment for multiple myeloma. Leuk Res, 2007,31 : 1027-1028.
  • 8Ohri A, Arena FP. Severe pulmonary complications in African- American patient after bortezomib therapy. Am J Ther ,2006, 13 553-555.
  • 9Zhou X, Sun C, Wang J, et al. Rapid fatal pulmonary complications in a Chinese patient after borlezomib treatment for ALK-negative anaplastie large-cell lymphoma. Clin Lymphoma Myeloma Leuk, 2010, 10:152-154.
  • 10Gupta A, Pandey A, Sethi S. Bortezomib-induced congestive cardiac failure in a patient with multiple myeloma. Cardiovasc Toxicol, 2012, 12:184-187.

引证文献6

二级引证文献14

中华内科杂志
2011年 第6期

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