还原黄G中间体合成新工艺

A New Synthesis Process of the Intermediate of Vat Yellow G

本文以1-氯-2-乙酰氨基蒽醌在1,3-二甲基-2-咪唑啉酮(DM I)介质中,在铜粉和苯酚催化作用下,于75℃进行乌尔曼反应,制备2,2′-二乙酰氨基-1,1′-联二蒽醌。通过改进工艺条件,使产品的收率由原来的55%左右提高到68%左右,降低了产品的成本。

In the presence of catalysts copper powder and phenol,2,2′-diacetamido-1,1′-bianthraquinone was synthesized from 1-chloro-2-acetylamino anthraquinone in 1,3-dimethyl-2-imidazolidinone by Ullmann reaction at 75 ℃.The yield of product was increased from 55% to 68% and the product cost was reduced by improving the synthesis process.