2007—2009年北京地区注射用抗菌药物给药频度的PK/PD模型分析

Dosing Frequencies of Antibiotics for Injection in Beijing Area from 2007 to 2009 Analyzed Using PK/PD Model

目的:研究2007—2009年北京地区注射用抗菌药物给药频度的合理性。方法:统计2007—2009年北京地区注射用抗菌药物的给药频度,并根据PK/PD模型进行分析。结果与结论:青霉素类、头孢菌素类和克林霉素合理性较差,氨基糖苷类和氟喹诺酮类合理性较好。

OBJECTIVE：To investigate the rationality of the dosing frequencies of antibiotics for injection in Beijing area from 2007 to 2009.METHODS：The dosing frequency of intravenous antibiotics in Beijing from 2007 to 2009 was statistically analyzed using PK/PD model.RESULTS ＆ CONCLUSION：The dosing frequencies of penicillins,cephalosporins and clindamycin were far from rational whereas those of aminoglycosides and quinolones were rational