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托吡酯致反复尿路结石1例 被引量:1

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摘要 托吡酯(topiramate,TPM)是1996年上市、由氨基磺酸酯取代单糖的新型广谱抗癫痫药,可单独应用或者辅助其他抗癫痫药,适用于成人和儿童癫痫的治疗。与其他抗癫痫药比较,TPM口服后吸收迅速、完全,药代动力学呈线性,主要经肾清除,半衰期长,1日服用1~2次即可维持有效血液药物浓度,蛋白结合率低。
出处 《中国医院用药评价与分析》 2011年第6期575-576,共2页 Evaluation and Analysis of Drug-use in Hospitals of China
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