腹腔镜胆囊切除术临床疗效观察

Clinical aeffect pbservation of laparoscopic cholecystectomy

目的观察腹腔镜胆囊切除术(LC)的临床应用效果。方法 150例患者随机分为LC组和开腹胆囊切除术(OC)组各75例。于术前1d,术后第1、2、3天进行外周血细胞分析,并观察2组术中情况、术后恢复和并发症发生情况。结果 2组术后白细胞数量均高于术前,差异均有统计学意义(P<0.05),LC组术后第1、2、3天白细胞均低于OC组,差异均有统计学意义(P<0.05)。LC组手术时间短于OC组,术中出血量少于OC组,切口小于OC组,差异均有统计学意义(P<0.05)。LC组抗生素应用、下床活动、术后排气及住院时间均短于OC组,差异均有统计学意义(P<0.05)。LC组发生并发症5例(6.7%),OC组为14例(18.7%),2组比较差异有统计学意义(P<0.05)。结论与OC相比,LC具有手术时间短,创伤小等优点,但应避免术后并发症。

Objective To observe the Clinical application effect of laparoscopic cholecystectomy（LC）.Methods 150 cases were randomly divided into LC group and open cholecystectomy（OC） group with 75 cases in each.The peripheral blood cells were analysed on 1 day preoperative and on 1、2、3 day postoperative ,and the condition of surgery,postoperative recovery and complications of 2 groups were observed.Results The number of leucocyte in both groups after surgery was higher than that in both groups before surgery,and the difference was statistically significant （P0.05）.The number of leucocyte of the LC group was lower than that of the OC group on 1、2、3 day after surgery,and the difference was statistically significant （P0.05 ）.Compared with the OC group,the operation time of the LC group was shorter,the blood loss was less and the incision size was smaller,the differences were statistically significant （P0.05）.The time of antibiotic application,ambulation ,exhaust postoperative and hospital stay of the LC group were respectively shorter than those of the OC group,and the differences were statistically significant（P0.05）.There were 5 patients with complication in the LC group （6.7%）,while 14 patients in the OC group （18.7%）,and the difference was statistically significant（P0.05）.Conclusion Compared with the OC group,the advantages of the LC group are as follows：shorter operation time and smaller trauma,but the postoperative complications should be avoided.