摘要
目的研究乳腺浸润性微乳头状癌(IMPC)临床病理特征。方法对26例IMPC组织标本行组织病理和免疫组化检测,观察其病理改变、淋巴转移情况。结果单纯IMPC仅3例;IMPC伴浸润性导管癌19例;其他类型共4例。免疫组化示癌细胞ER阳性率73·1%,PR阳性率46·2%,Her-2阳性率76·9%,CD31阳性率50%,EMA,CK7阳性率100%)。IMPC淋巴管浸润率为76·9%,淋巴结转移率为73·1%。结论 IMPC具有高度的淋巴结转,组织学形态及免疫组化相结合可诊断此病。
Objective To research the clinical features of breast invasive micropapillary carcinoma.Methods 26 cases of IMPC of pathological tissue specimens and immunohistochemistry were detected observed the pathological changes in lymphatic metastasis.Results Only3 cases of pure IMPC,IMPC with infiltratingductal carcinoma in 19 cases,other types of 4 cases.ER immunohistochemistry showed the positive rate of cancer 73·1%,PR positive rate of46·2%,Her-2 positive rate of76·9%,CD31-positive rate of50%,EMA,CK7-positive rate of 100%）.IMPC lymphatic infiltration rate was 76·9%,lymph node metastasis rate was 73·1%.Conclusion IMPC with a high degree of metastasis of lymph nodes,histological and immunohistochemical diagnosis of the disease can be combined.
出处
《中国现代药物应用》
2011年第10期16-17,共2页
Chinese Journal of Modern Drug Application
关键词
浸润性微乳头状癌
病理
免疫组织化学
Invasive micropapillary carcinoma
Pathological
Immunohistochemical
