alpha B-crystallin与肿瘤的研究进展
被引量:1
摘要
alpha B-crystallin属于小热休克蛋白家族,具有分子伴侣作用,能够帮助未折叠蛋白正确折叠,防止变性蛋白质聚集,保持DNA的稳定,从而维持细胞的正常结构和功能。此外,alpha B-crystallin还与细胞凋亡的关系密切,
出处
《中国肿瘤临床与康复》
2011年第3期282-284,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
参考文献21
-
1刘双,肖献忠.αB-晶体蛋白的功能与疾病[J].生命的化学,2005,25(2):89-91. 被引量:11
-
2Arrigo AP, Simon S, Gibert B, et al. Hsp27 ( HspB1 ) and al- phaB-erystallin (HspBS) as therapeutic targets[J]. FEBS Lett, 2007,581 ( 19 ) :3665-3674.
-
3Masilamoni JG, Jesudason EP, Baben B, et al. Molecular chap- crone alpha-crystallin prevents detrimental effects of neuroinflam- mation [ J ]. Biochim Biophys Acta, 2006,1762 ( 3 ) :284 -293.
-
4Inagaki N, FIayashi T, Arimura T, et al. Alpha B-erystallin mu- tation in dilated cardiomyopathy[ J]. Biochem Biophys Res Com- mun, 2006,342 ( 2 ) : 379 -386.
-
5Kumarapeli AR, Su H, Huang W, et al. Alpha B-crystallin sup- presses pressure overload cardiac hypertrophy [ J ]. Circ Res, 2008,103(12) :1473-1482.
-
6Singh BN, Rao KS, Rao ChM. Ubiquitin-proteasome-mediated degradation and synthesis of MyoD is modulated by alphaB-crys- taliin, a small heat shock protein, during muscle differentiation [J]. Biochim Biophys Acta, 2010, 1803(2) :288-299.
-
7Joo-Hyun Shin, Seung-Woo Kim, Chae-Moon Lim, et al. aB- crystallin suppresses oxidative stress-induced astrocyte apoptosis by inhibiting caspase-3 activation[ J]. Neurosci Res, 2009, 64: 355-361.
-
8Liu S, Li J, Tao Y, et al. Small heat shock protein alphaB-crys-tallin binds to p53 to sequester its translocation to mitochoridria during hydrogen peroxide-induced apoptosis [ J ]. Biochem Bio- phys Res Commun, 2007, 354 ( 1 ) : 109-114.
-
9Mao YW, Liu JP, Xiang H, et al. Human alphaA-and alphaB- crystallins bind to Bax and Bcl-X(S) to sequester their transloca- tion during staurosporine-induced apoptosis [ J ]. Cell Death Dif- fer, 2004, 11(5) :512-526.
-
10Li DW, Liu JP, Mao YW, et al. Calcium-activated RAF/MEK/ ERK signalin$ pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of IIAS activa- tion[J]. Mol Biol Cell, 2005, 16(9) :4437-4453.
二级参考文献20
-
1Somasundaram T et al. J Biol Chem. 2004. 279:44497-44503.
-
2Yan LJ et al. EMBO J, 2002, 21:5164-5172.
-
3Webster KA. Circ Res, 20031 92:130-132.
-
4Verschuure Pet al. J Mol Cell Cardiol. 2002, 34:117-128.
-
5Bullard Bet al. J Biol Chem, 2004. 279:7917-7924.
-
6Morrison LE et al. Am J Physiol Heart Circ Physiol, 2004, 286:H847-855.
-
7Koh TJ et al. Am J Phvsiol Cell Phvsiol. 2004. 286. C713-722.
-
8Martin JL et al. Am J Physiol Heart Cite Physio), 2002, 283:H85-91.
-
9Morrison LE et al. Cite Res, 2003, 92:203-211.
-
10Bai F et al. J Biol Chem, 2003, 278:36876-36886.
共引文献10
-
1李立宇,王林.αB-晶体蛋白对乳鼠心肌细胞在缺氧/复氧条件下的表达及保护作用的实验研究[J].中国城乡企业卫生,2010,25(3):92-94.
-
2周建美,邹定全,冉珂,常业恬.2-氯环戊腺苷预处理延迟相对兔缺血-再灌注损伤心肌αB-晶状体蛋白的影响[J].临床麻醉学杂志,2011,27(3):284-286. 被引量:1
-
3周建美,邹定全,冉珂,常业恬.腺苷A1受体激动剂预处理兔延迟相心肌蛋白质组学分析[J].中南大学学报(医学版),2011,36(10):999-1002. 被引量:1
-
4刘志涛,张辉,边立娟,谢明明,房学迅.αB-晶状体蛋白在不同周龄正常大鼠晶状体中的表达[J].中国实验诊断学,2012,16(3):384-387. 被引量:4
-
5全宏志,唐瞻贵,赵丽莉,姚志刚,王柏盛,谢尚.αB-crystallin在口腔疣状癌中的表达及其抗凋亡机制的初步研究[J].上海口腔医学,2012,21(4):432-436. 被引量:2
-
6张凯丽,田志胜,王树峰.a-B晶体蛋白在三阴性乳腺癌中的表达及靶向治疗意义[J].中国肿瘤临床,2013,40(18):1106-1110. 被引量:5
-
7马艳霞,孙韬,郭政.SP对NE诱导的体外培养大鼠心肌细胞凋亡的影响及机制[J].山西医科大学学报,2015,46(4):289-292. 被引量:3
-
8陈向丽,王铜,冯红旗,侯杰,甄荣霞,徐春艳,王哲.慢型克山病患者血清中αB晶体蛋白表达及意义的研究[J].中国地方病防治,2016,31(10):1081-1083.
-
9马艳霞,郭政.去甲肾上腺素对原代培养大鼠心肌细胞的凋亡率及相关蛋白的影响[J].山西医科大学学报,2017,48(12):1213-1217. 被引量:2
-
10张英杰,王鹏,张美英,隋凯悦,路芳.益胃汤对初老雌性大鼠下丘脑作用的差异蛋白分析[J].天津中医药,2018,35(10):769-773. 被引量:1
同被引文献19
-
1Wu H,Xu H,Zhang S,et al. Potential therapeutic target and independent prognostic marker of TROP2 in laryngeal squa- mous cell carcinoma [J]. Head Neck, 2013,35 (10) : 1373- 1378.
-
2Jemal A,Siegel R,Ward E,et al. Cancer statistics,2009 [J]. CA Cancer J Clin, 2009,59 (4) : 225-249.
-
3Hoffman HT, Porter K, Karnell LH, et al. Laryngeal cancer in the United States:changes in demographics,patterns of care,and survival [J]. Laryngoscope,2006,116(9 Pt 2 Sup- pl 111):1-13.
-
4Boyle P,Ferlay J. Cancer incidence and mortality in Eu- rope [J]. Ann Oneol,2005,16(3):481-488.
-
5Chin D, Boyle GM,Williams RM, et al. AlphaB-crystallin, a new independent marker for poor prognosis in head and neck cancer [ J]. Laryngoscope,2005,115(7) :1239-1242.
-
6Malin D,Petrovie V, Strekalova E, et al. o~B -crystallin : Portrait of a malignant chaperone as a cancer therapeutic target [J]. Pharmacol Ther, 2016,160 : 1-10.
-
7Cherneva R,Petrov D,Georgiev O,et al. Expression pro- file of the small heat shock protein alphaB-crystallin in operated on non small cell lung cancer patients:clinical implication [J]. Eur J Cardiothorac Surg,2010,37( 1 ):44- 50.
-
8Tang Q,Liu YF,Zhu XJ,et al. Expression and prognostic sig- nificance of the alphaB-crystallin gene in human hepatocel- lular carcinoma [J]. Hum Pathol, 2009,40 (3) : 300-305.
-
9Moyano JV, Evans JR,Chen F,et al. AlphaB-crystallin is a novel oncoprotein that predicts poor clinical outcome in breast cancer [J]. J Clin Invest, 2006,116(1):261-270.
-
10Mineva I,Stamenova M,Gartner W,et al. Expression of the small heats hock protein alphaB-crystallin in term human placenta [J]. Am J Reprod Immunol, 2008,60 (5): 440-448.
-
1胡文忠.Alpha B-crystallin基因在人胶质瘤中的表达[J].交通医学,2007,21(1):20-21.
-
2仲楼.Alpha B-crystallin在肺鳞状细胞癌中的表达及意义[J].临床医学,2012,32(2):59-60.
-
3牛昊书,陈吉.HSP70与胃癌关系的研究进展[J].疾病监测与控制,2012,6(11):672-673. 被引量:1
-
4杭晓声,汪道远,王卫理,李莉华.Alpha B-crystallin基因在结肠癌组织中的表达及其意义[J].肿瘤防治研究,2009,36(2):140-143. 被引量:1
-
5沈文香,李海,沈刚,徐海源,周丽娜.Alpha B-crystallin基因在胃癌组织中的表达及其意义[J].交通医学,2008,22(2):125-127. 被引量:1
-
6高树峰,徐莲,张少容,李黎,汪美群,刘月辉.钙网蛋白与肿瘤治疗[J].基础医学与临床,2013,33(11):1504-1507. 被引量:2
-
7黄晓勇,柯爱武,施国明,周俭.Alpha B-crystallin蛋白Ser^(59)磷酸化在肝细胞肝癌中的意义[J].中国临床医学,2015,22(6):734-737.
-
8郑华.内质网应激介导的细胞死亡与肿瘤治疗进展[J].肿瘤防治研究,2013,40(2):197-200. 被引量:4
-
9刘学铭,楼江燕.内质网分子伴侣葡萄糖调节蛋白94与肿瘤研究进展[J].中华妇幼临床医学杂志(电子版),2008,4(2):64-66. 被引量:2
-
10新的自动化工具可分类并描述蛋白质[J].基础医学与临床,2005,25(3):226-226.