重度子痫前期患者胎盘组织趋化因子及其受体的表达和意义
被引量:5
摘要
妊娠免疫耐受是正常妊娠时母体形成的一种特殊类型的外周免疫耐受,保护作为半同种移植物的胎儿不被母体免疫系统排斥而成功妊娠,这有赖于免疫活性细胞的分化及功能调整。趋化因子(Chemokine,CK)及其受体不但直接参与了淋巴细胞的增殖和活化,还促进母胎界面T淋巴细胞及NK细胞的游走和活化,可影响一系列的细胞活动,包括粘附、血管牛成和扩散[1]。
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
2011年第6期565-566,共2页
Chinese Journal of Immunology
参考文献8
-
1Hamaan N J, Salamonsen L A. Role of chemokines in the endometrium and in embryoimplantation[ J ]. Curr Opin Obstet Gynecol, 2007 ; 19 (3) : 266- 271.
-
2黄煜,李大金,王明雁,程海东.趋化因子及其受体在人早孕绒毛组织中的表达特征及意义[J].中华妇产科杂志,2006,41(6):399-402. 被引量:8
-
3Pijnenborg R. The uterine spiral artery in humma pregnancy: facts mad controversies[ J]. Placenta, 2006 ; 27 : 939-958.
-
4Carvaiho-Gaspar M, Billing J S, Spriewald B Met al. Chemokine gene ex- pression during allograft rejection: Comparison of two quantitative PCR techniques [ J ]. J Immunol Methods, 2005 ; 301 ( 1-2 ) : 41-52.
-
5Lasagni L, Francalanci M, Ammnziato F et al. An ahcrnatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth in- duced by IP-10, Mig and I-TAC, and acts as functional receptor for platelet factor 4 [ J ]. J Exp Med, 2003; 197( 11 ) : 1537-1549.
-
6Chandrasekar B, Bysani S, Mummidi S. CXCL16 signals via Gi phos- phatidylinositol 3- kinase, Akt, 1 kappa B kinase, and nuclear factor-kappa B and induces cell-cell adhesion and aortic smooth muscle cell prolifera- tion[J] .J Biol Chem,2004;279:3188-3196.
-
7Shimaoka T, Nakaymna T, Fukmnoto Net al. Cell surfacemachored SR- PSOX/CXC chemokine receptor 6-expressing cells [ J ]. J luk Biol, 2004 ; 75,267-274.
-
8Huang Y,Zhu X Y, Du M R et ol. Chemokine CXCL 16, a scavenger re- ceptor induces proliferation and invasion of first-trimester human trophoblast cells in an antrine manner[J] .Hum Reprod,2006;21 : 1083-1091.
二级参考文献11
-
1孙飞,姚元庆,李东红,尹国武,姜锋,王文勇,王淑芳.缺氧诱导因子1α在妊娠高血压综合征患者胎盘组织中的表达[J].中华妇产科杂志,2004,39(7):442-445. 被引量:4
-
2Douglas GC,Thirkill TL,Sideris V,et al.Chemokine receptor expression by human syncytiotrophoblast.J Reprod Immunol,2001,49:97-114.
-
3Hoffman TL,Stephens EB,Narayan O,et al.HIV type I envelope determinants for use of the CCR2b,CCR3,STRL33,and APJ coreceptors.Proc Natl Acad Sci U S A,1998,95:11360-11365.
-
4Nakayama T,Hieshima K,Izawa D,et al.Cutting edge:profile of chemokine receptor expression on human plasma cells accounts for their efficient recruitment to target tissues.J Inununol,2003,170:1136-1140.
-
5Shimaoka T,Nakayama T,Kume N,et al.Cutting edge:SRPSOX/CXC chemokine ligand 16 mediates bacterial phagocytosis by APCs through its chemokine domain.J Immunol,2003,171:1647-1651.
-
6Chandrasekar B,Bysani S,Mummidi S.CXCL16 signals via Gi,phosphatidylinositol 3-kinase,Akt,I kappa B kinase,and nuclear factor-kappa B and induces cell-cell adhesion and aortic smooth muscle cell proliferation.J Biol Chem,2004,279:3188-3196.
-
7Shimaoka T,Nakayama T,Fukumoto N,et al.Cell surfaceanchored SR-PSOX/CXC chemokine ligand 16 mediates firm adhesion of CXC chemokine receptor 6-expressing cells.J Leukoc Biol,2004,75:267-274.
-
8Wu X,Li DJ,Yuan MM,et al.The expression of CXCR4/CXCL12 in first-trimester human trophoblast cells.Biol Reprod,2004,70:1877-1885.
-
9Huang Y,Zhu XY,Du MR,et al.Chemokine CXCL16,a scavenger receptor,induces proliferation and invasion of firsttrimester human trophoblast cells in an autocrine manner.Hum Reprod,2006,21:1083-1091.
-
10吴霞,李大金,袁敏敏,王明雁,程海东.人早孕期绒毛组织和滋养细胞趋化因子受体转录水平[J].中国免疫学杂志,2004,20(1):53-58. 被引量:10
共引文献7
-
1李大金.趋化因子在人母-胎界面的整合性调节作用[J].现代免疫学,2009,29(1):1-5.
-
2张树成,乔雷,高红.利用RNA干扰抑制CXCR4基因表达对乳腺癌细胞转移和侵袭能力的影响[J].中华外科杂志,2007,45(7):473-475. 被引量:7
-
3熊苗,屠菊红,赵爱民.母胎界面趋化因子及其受体的研究进展[J].中国妇幼保健,2007,22(23):3315-3317.
-
4朱剑文,邹丽,何明,周燕,赵茵.无症状沙眼衣原体和解脲支原体感染对早孕绒毛滋养细胞表达CXCL12/CXCR4的影响[J].华中科技大学学报(医学版),2007,36(6):768-772. 被引量:1
-
5唐若澜,魏麓云.CXCL16在相关疾病中的作用机制研究进展[J].社区医学杂志,2012,10(4):50-52. 被引量:4
-
6宋英娜,杨剑秋,刘俊涛,黄赛琼.早发型重度子痫前期孕妇胎盘组织中差异表达基因的研究[J].中华妇产科杂志,2014,49(7):501-505. 被引量:7
-
7施旖旎.植入性胎盘组织滋养细胞中趋化因子CXCL-12及其受体CXCR-4 CXCR-7的表达和意义[J].中国妇幼保健,2021,36(1):172-175.
同被引文献39
-
1乐杰.妇产科学[M].7版.北京:人民卫生出版社,2010:366.
-
2Gkhan Y,Kemal G,Halil A.Comparison of perinatal and maternal outcomes of severe preeclampsia, eclampsia, and HELLP syndrome. Journal of the Turkish-German Gynecological Association, 2011,12 (2):356.
-
3Cackovic M, Buhimschi CS,Zhac G, et al.Fractional excretion of tu- mot necrosis factor- alpha in women with severe preeclampsia.Ob- stetrics & Gynecology, 2008,112( 1 ) : 93-100.
-
4李宛真.循证护理在妊娠高血压综合征患者中的应用效果评价[J].中国实用护理杂,2011,27(5):37-38.
-
5郑修霞.妇产科护理学[M].4版.北京:人民卫生出版社,2010:230.
-
6Conti E, Zezza L, Ralli E, et al. Growth factors in preeclampsia: a vascular disease model. A failed vasodilation and angiogenic challenge from pregnancy onwards? [ J]. Cytokine Growth Factor Rev,2013,2d(5) :411-425.
-
7Gennari-Moser C, Khankin EV, Escher G, et al. Vascular endothelial growth factor-A and aldosterone: relevance to normal pregnancy and preeclampsia [ J ]. Hypertension, 2013,61 ( 5 ) : 1111-1117.
-
8Laszlo KD, Liu XQ, Svensson T, et al. Psychosocial stress related to the loss of a close relative the year before or during pregnancy and risk of preeclampsia[ J]. Hypertension,2013,62 ( 1 ) :183-189.
-
9Li Z,Ye R,Zhang L,et al. Folic acid supplementation during early pregnancy and the risk of gestational hypertension and preeclampsia [ J ]. Hypertension, 2013,61 (4) : 873-879.
-
10Powis KM, McElrath TF, Hughes MD, et al. High viral load and elevated angiogenie markers associated with increased risk of pre-eclampsia among women initiating highly active antiretroviral therapy in pregnancy in the Mma Bana study, Botswana [ J ]. J Acquir Immune Defic Syndr,2013,62(5) :517-524.
引证文献5
-
1徐树霞.整体护理干预在重度子痫前期患者中应用的效果评价[J].中国实用护理杂志,2012,28(19):40-41. 被引量:20
-
2王巧玲,刘小媚.预见性护理对重度子痫患者心情及分娩结局的影响[J].中国基层医药,2014,21(2):312-314. 被引量:9
-
3王春慧.重度子痫前期患者剖宫产的临床处理体会[J].基层医学论坛,2014,18(22):2925-2926. 被引量:2
-
4许旭,朱启英.维吾尔族早发型子痫前期患者血清晚期氧化蛋白产物和胱抑素C水平及其与妊娠结局的相关性[J].中国免疫学杂志,2014,30(12):1701-1704. 被引量:9
-
5倪琰琰,程蔚蔚.早发型子痫前期发病机制的研究进展[J].山东医药,2016,56(8):101-104. 被引量:32
二级引证文献71
-
1李莉君.低分子量肝素与硫酸镁联合治疗早发型先兆子痫患者的临床效果[J].世界临床医学,2017,11(16):138-138.
-
2于建萍,高章萍.护理干预对产科弥散性血管内凝血的预防效果[J].血栓与止血学,2013,19(3):140-141. 被引量:1
-
3谢雪珠,李华飞,黄洁琼.新生儿颅内出血相关因素分析及护理干预的预防效果[J].齐齐哈尔医学院学报,2013,34(12):1826-1827. 被引量:5
-
4刘平,何少斌.舒适护理在子痫前期剖宫产患者术后护理中的应用[J].国际护理学杂志,2013,32(11):2411-2413. 被引量:4
-
5王巧玲,刘小媚.预见性护理对重度子痫患者心情及分娩结局的影响[J].中国基层医药,2014,21(2):312-314. 被引量:9
-
6徐晓青.早发型重度子痫前期孕妇预后的护理分析与探讨[J].实用临床医药杂志,2014,18(18):131-133. 被引量:9
-
7刘滢.护理人文关怀对妊娠高血压患者妊娠结局及产后恢复的影响[J].中国伤残医学,2014,22(23):195-197. 被引量:1
-
8王瑾.剖宫产护理实施整体护理的效果探究[J].中外医疗,2015,34(7):155-156. 被引量:6
-
9梁婧,邓童宁,玉丽丽,吕宁,甘江丽.子痫前期患者血清中AOPP、IMA水平及其与肾功能的关系[J].疑难病杂志,2015,14(9):953-955. 被引量:4
-
10厉珍,刘小媚.规范化护理干预对早发型重度子痫前期患者预后的影响[J].中国基层医药,2015,22(18):2874-2876. 被引量:13
-
1肖世金,赵爱民.趋化因子及其受体在妊娠免疫耐受中的作用[J].上海交通大学学报(医学版),2009,29(9):1116-1119. 被引量:5
-
2熊苗,屠菊红,赵爱民.母胎界面趋化因子及其受体的研究进展[J].中国妇幼保健,2007,22(23):3315-3317.
-
3齐丹,侯莉莉,谈勇,吕珊珊.中药调控妊娠免疫耐受的研究进展[J].中国中西医结合杂志,2015,35(9):1142-1145. 被引量:4
-
4杨冬梅,李慕军.HLA-G与妊娠免疫耐受[J].中国免疫学杂志,2007,23(5):479-480.
-
5肇静娴,曾耀英.母胎界面免疫耐受的细胞及分子基础研究进展(简介)[J].暨南大学学报(自然科学与医学版),2000,21(4):81-83.
-
6马兴璇,刘春明.CD4^+CD25^+调节性T细胞与妊娠关系的研究进展[J].中国基层医药,2015,22(12):1902-1903.
-
7张钰,李奕.CXCL12,CCL2,RANTES及其受体与妊娠免疫耐受[J].国际生殖健康/计划生育杂志,2011,30(5):420-424. 被引量:5
-
8雷艳君,寇小格,袁育康,范桂香.Fas/FasL系统与妊娠免疫耐受[J].国外医学(妇幼保健分册),2002,13(3):103-105.
-
9靳二辉,王趁芳,乔恩美,胡倩倩,刘德义,顾有方,金光明,李升和.IL-35及其免疫调节作用与妊娠免疫耐受的关系[J].安徽科技学院学报,2012,26(6):5-9.
-
10陈赛英,季晓辉.蜕膜树突状细胞与妊娠耐受[J].国外医学(妇产科学分册),2007,34(5):338-342.