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激素对骨髓基质细胞分化的影响及与股骨头坏死的关系 被引量:7

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摘要 股骨头坏死(osteonecrosis of femoral head,ONFH)是一种破坏性退行性疾病,病情进展可以发生软骨下骨和关节面软骨的塌陷。该病多发生于青壮年,平均发病年龄38岁。如果不采取积极的治疗,绝大多数患者最终都需要行全髋关节置换。目前提及的病因有如下理论:激素性、酒精性、创伤性及一些特发性;发病机制有脂肪栓塞、血管内凝血以及骨内压增加等假说,但是这些假说并无任何一种完全得到公认。
出处 《中国矫形外科杂志》 CAS CSCD 北大核心 2011年第13期1100-1103,共4页 Orthopedic Journal of China
基金 国家自然科学基金面上项目(编号:30772202/C1607) 教育部博士点基金新教师基金(编号:850-20070610005)资助
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参考文献35

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二级参考文献69

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