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帕罗西汀对抑郁模型大鼠海马各区p-CREB的影响 被引量：4

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摘要 帕罗西汀属于5-HT再摄取抑制（SSRIs），它能够特异性抑制中枢神经系统内的5-HT；是临床常用的一线抗抑郁剂，抗抑郁的疗效较为肯定。但是临床上患者服用了此类抗抑郁药物后中枢单胺类浓度迅速提高，抑郁症的临床症状的缓解常常需要经过几周甚至更长的时间。因而提示，抗抑郁药的作用靶点可能另有所在。
作者 郑晖 任迎涛 崔立谦 马光瑜 宋卉
机构地区 广东食品药品职业学院心理辅导中心 广州医学院第一附属医院精神医学科
出处 《中华行为医学与脑科学杂志》 CAS CSCD 北大核心 2011年第6期497-498,共2页 Chinese Journal of Behavioral Medicine and Brain Science
基金 广东省科技计划项目（20088030301194）
关键词 帕罗西汀 P-CREB 大鼠海马 抑郁模型 中枢神经系统 抗抑郁药物 临床症状 5-HT
分类号 R-332 [医药卫生] R74 [医药卫生—神经病学与精神病学] R9 [医药卫生—药学]
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参考文献8

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  • 2吴枫.噻萘普汀与碳酸锂对慢性应激抑郁模型大鼠海马pCREB表达的影响[J].中华行为医学与脑科学杂志,2011,20(5):385-387. 被引量：8
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二级参考文献13

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  • 2郑晖,马光瑜,许崇涛.帕罗西汀对抑郁模型大鼠不同脑区环磷酸腺苷反应元件结合蛋白的影响[J].中华精神科杂志,2007,40(2):113-116. 被引量：7
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共引文献18

同被引文献58

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中华行为医学与脑科学杂志
2011年 第6期

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