2型糖尿病患者血糖升高时眼调节力变化的研究

Changes of eye accommodation in patients with type 2 diabetes mellitus when blood glucose raises

目的探讨2型糖尿病患者血糖升高时眼调节力的变化。方法 选取首诊确诊为2型糖尿病的42例患者作为糖尿病组;血糖≤6.0mmol.L-1正常人群48例作为对照组。屈光不正者需进行屈光不正的检查及矫正。矫正视力后,所有受试者行单眼调节幅度、单眼正相对调节力、单眼负相对调节力、双眼调节滞后量、单眼及双眼调节灵活度的检测。结果 糖尿病组调节幅度、正相对调节力、负相对调节力、调节滞后量分别为(4.94±1.28)D、(-1.27±0.33)D、(2.27±0.42)D、(0.59±0.08)D,对照组分别为(6.60±1.54)D、(-2.41±0.53)D、(2.29±0.49)D、(0.62±0.09)D;糖尿病组左、右眼及双眼调节灵活度分别为(2.57±0.67)cpm、(2.40±0.73)cpm、(2.31±0.53)cpm,对照组分别为(11.42±1.89)cpm、(11.70±1.99)cpm、(8.69±2.08)cpm。相比对照组,糖尿病组调节幅度、正相对调节力、左、右眼及双眼调节灵活度均降低,差异均有统计学意义(均为P<0.01),而负相对调节力、调节滞后量差异均没有统计学意义(均为P>0.05)。结论 2型糖尿病患者血糖升高时,单眼调节幅度、单眼正相对调节力、左、右眼及双眼调节灵活度均降低,而单眼负相对调节力及双眼调节滞后量没有明显差异。

Objective To investigate changes of eye accommodation in patients with type 2 diabetes mellitus when blood glucose raises. Methods About 42 cases with type 2 diabetes mellitus were selected as diabetic group, and 48 normal people with glucose be and less than 6.0 mmol · L-1 were collected as control group. Cases with ametropia were taken examination and correction. After correction, monocular accommodation amplitude （ AA）, positive relative accommodations （ PRA）, negative relative accommodation （NRA） ,binocular lag of accommodation （LOA）, monocular and binocular accommodation facility （AF） were detected. Results AA, PRA, NRA and LOA were （4.94±1.28）D,（ -1.27 ±0.33）D, （2, 27 ±0.42）D and （0.59 ±0.08） D in diabetic group,（6.60 ±1.54）D,（ -2.41 ±_0.53）D,（2.29 ±0.49） D and （0.62 ±0.09）D in control group. AF of left eyes,fight eyes and both eyes were （2.57 _±0.67 ） cpm, （2.40 ± 0.73 ） cpm and （2.31 ± 0.53 ） cpm in diabetic group, （ 11. 42 ± 1.89 ） cpm, （ 11.70 ± 1.99 ） cpm and （ 8, 59 ± 2.08 ） cpm in control group. Compared with control group, AA, PRA, AF of left eyes ,right eyes and both eyes increased（ all P 〈0.01 ） ,but no difference was found in NRA or LOA （ all P 〉 0.05 ）. Conclusions Monocular AA, PRA, AF of right eyes,left eyes and both eyes increase in patient with type 2 diabetes mellitus, but no difference is found in monocular NRA or binocular LOA.