摘要
BRAF^T1799A基因突变作为一个新的、有效的分子标记物,在乳头状甲状腺癌(PTC)的辅助诊断、评估预后、指导治疗等方面的重要地位已经被越来越多的研究证实。本文将对这一突变在PTC临床诊治中的意义作以综述。
Significant progress has been made toward understanding the tumorigenic role and clinical significance of the T1799A B-type Raf kinase (BRAF)mutation in papillary thyroid cancer (PTC). With these advances, it has become clearer that BRAF mutation will likely have significant impact on the clinical management.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2011年第6期525-528,共4页
Chinese Journal of Endocrinology and Metabolism
基金
国家自然科学基金(30801120)