基于健康风险的三氯杀螨醇生产设备表面污染物筛选值推算的初步研究

Preliminary Study on Derivation of Health Risk-based Surface Screening Levels of Contaminants for Dicofol Manufacturing Equipment

运用确定性和概率性人体健康风险评估的方法,推算一般工业暴露情景和拆卸清理暴露情景下三氯杀螨醇生产设备表面污染物的筛选值。结果表明:p,p′-滴滴涕、p,p′-滴滴滴和p,p′-滴滴依基于确定性风险评估的设备表面筛选值在一般工业暴露情景下分别为0.224 mg/m2、0.214 mg/m2和0.151 mg/m2,在拆卸清理暴露情景下分别为9.68 mg/m2、10.7 mg/m2和7.57 mg/m2;基于蒙特卡罗概率性风险评估的表面筛选值更为保守;不确定性分析表明从手到口部发生次数、接触表面频率和可供摄入的皮肤有效表面积等为敏感参数。

Deterministic and probabilistic human health risk assessment approaches were used to derive the surface screening levels of contaminants for Dicofol manufacturing equipment under industrial and demolition exposure scenarios.It was found that the surface screening levels of p,p′-DDT,p,p′-DDD and p,p′-DDE based on the deterministic calculation under the industrial exposure scenario were 0.224 mg/m2,0.214 mg/m2 and 0.151 mg/m2,respectively,while the surface screening levels of these pollutants under the demolition exposure scenario were 9.68 mg/m2,10.7 mg/m2 and 7.57 mg/m2,respectively.Surface screening levels derived by Monte Carlo-based probabilistic risk assessment were more conservative under the same scenarios.Uncertainty analysis indicated that HTME,EV and SAg were sensitive parameters.