心肝宝胶囊治疗血吸虫病肝纤维化

Therapeutic effect of capsule Xinganbao on schistosomal hepatocirrhosis

治疗组62例血吸虫病肝硬化患者口服心肝宝胶囊,剂量为每次4粒,日3次;对照组56例,口服复合维生素B、护肝片及利尿剂等。疗程均为6个月。心肝宝胶囊治疗后血清透明质酸酶,层黏蛋白和Ⅲ型前胶原均明显下降,两组差异有统计学意义(P<0.05),治疗后肝功能和肝脾影像学两组均有所改善,但差异无统计学意义。心肝宝胶囊有一定抗血吸虫性肝纤维化作用。

A total of 118 patients with schistosomal hepatocirrhosis were divided into an experiment group （62 cases） and a control group （56 cases）, and the former received capsule Xinganbao and the latter received conventional medicine for 6 months. The reductions of serum HA, LN and PCIII were more notable in the experiment group than in the control group （P 0.05）. The clinical symptoms, physical signs, and liver function improved in both groups, and there were no significant differences between two groups. In conclusions, capsule Xinganbao has a good effect on hepatic fibrosis.