摘要
寄生虫病防治策略之一是研制安全有效的疫苗,DNA疫苗是近10多年发展起来的新型疫苗。近年来寄生虫病DNA疫苗研究取得了很大进展。本文就DNA疫苗的免疫机理、构建与优化、佐剂、递送途径,以及疟疾、血吸虫病、囊尾蚴病、弓形虫病等重要寄生虫病DNA疫苗的研究进展作一综述。
One of the effective prevention and treatment strategies to parasitosis is to develop safe and effective vaccines. The DNA vaccine is a new kind of vaccine developed in last 10 years. In recent years, many advances in DNA vaccines against parasitosis have been made. This article reviews the advances in the mechanism, construction , optimization , adjuvants and delivery ways of DNA vaccines and the advances in the study of DNA vaccines against some parasitosis including malaria, schistosomiasis, cysticercosis and toxoplasmosis in recent years.
出处
《中国血吸虫病防治杂志》
CAS
CSCD
北大核心
2011年第3期340-344,共5页
Chinese Journal of Schistosomiasis Control
基金
国家自然科学基金(30600518)
卫生部寄生虫病预防与控制技术重点实验室招标课题(WK008-002)
