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imcroRNAs对免疫系统作用的研究进展 被引量:1

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摘要 microRNA(miRNA)s是一类长约20-22nt的单链、非编码小RNA,广泛存在于病毒、线虫、植物、动物体内。成熟miRNAs可通过特异性碱基配对识别靶mRNA,使之降解或抑制其翻译,从而抑制蛋白质的合成,调控基因表达。miRNAs于1993年首次被发现,
出处 《上海预防医学》 CAS 2011年第6期308-310,共3页 Shanghai Journal of Preventive Medicine
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  • 1Suarez Y, Fernandez - Hernando C, Pober J S,et al. Dicer dependent micreRNAs regulate gene expression and functions in human endothelial ceils[ J]. Cire Res,2007,100(8) :1164 - 1173.
  • 2Chen C Z,Ei L. Lodish H F,et al. MicroRNAs modulate hematopoietic lineage differentiation[ J]. Science, 2004,303:83 - 86.
  • 3Li QJ, Chau J ,Ebert PJ, et al. miR- 181 a is an intrinsic modulator of T cell sensitivity and selection. Cell[ J ] ,2007,129 : 147 - 161.
  • 4Liston A, Lu LF, OCarroll D, Tarakhovsky A, Rudensky AY. Dicerdependent microRNA pathway safeguards regulatory T cell function [ J ]. J Exp Med 2008,205 : 1993 - 2004.
  • 5Rodriguez A, Vigorito E, Clare S, et al. Requirement of bic/microRNA - 155 for normal immune function[ J]. Science, 2007,316:608 -601 i.
  • 6Huang B, Zhao J, Lei Z, et al. miR - 142 - 3 prestricts cAMP production in CIM + CD25 - Tcells and CD4 +CD25+ TREG cells by targetingAC9 mRNA. EMBO Rep. 2009;10:180 - 185.
  • 7Neilson JR, Zheng G X, Burge C B, et al. Dynamic regulation of miRNA expression in ordered stages of cellular development [ J ]. Genes Dev, 2007,21 (5) :578 - 589.
  • 8Xiao C, Calado DP, Galler G, et al. MiR - 150 controls B cell differen- tiation by targeting the transcription factor c - Myb[ J ]. Cell, 2007,131 : 146 - 159.
  • 9Rao DS, O' ConneU RM, Chaudhuri AA, et al. MicroRNA - 34a perturbs B lymphocyte development by repressing the forkhead box transcription factor Foxpl [ J ]. Immunity ,2010,33:48 - 59.
  • 10O' connell R M, Rao D S, Chaudhuri A A, et al. Sustained expression of microRNA - 155 in hematopoietic stem cells causes a myeloprolifera' tire disorder[ J]. J Exp Med, 2008,205:585 -594.

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