摘要
目的:研究妇科恶性肿瘤患者5项凝血指标的变化及其临床意义。方法:术前测定101例妇科恶性肿瘤患者(宫颈癌28例,卵巢癌35例,子宫内膜癌38例)的血小板(PLT)、血浆凝血酶原时间(PT)、部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)并与89例妇科良性肿瘤患者(子宫肌瘤45例,卵巢囊肿44例)进行比较。结果:妇科恶性肿瘤患者的FIB及PLT水平与妇科良性肿瘤组相比明显增高(P<0.01);而APTT、PT、TT水平与妇科良性肿瘤组相比差异无统计学意义(P>0.05),同时分期为Ⅲ~Ⅳ期晚期恶性肿瘤患者的血浆FIB及PLT水平均高于Ⅰ~Ⅱ期的患者(P<0.01)。结论:妇科恶性肿瘤患者体内存在着异常的血液高凝状态。
Objective: To study the changs of coagulation parameter in patients with gynecologic malignant tumor and its clinical significance.Methods: Detect the PLT,PT,APTT,TT and FIB levels of 101 gynecologic malignan tumors(including 28 cervical carcinomas,35 ovarian carcinomas,38 uterus intimal carcinomas) and 89 gynecologic tumors(inciuding 45 uterine myomas,44 oarian cysts).Results: As compared with normal terms,APTT,PT and TT were no significanty different while FIB and PLT were significantly higher(P〈0.01)in gynecologic malignant tumor patients.FIB and PLT of term Ⅲ to Ⅳ were higher than that in term Ⅰ to Ⅱ(P〈0.01).Conclusion: There are an abnomal balance between hyper-coagulation in patients with gynecologic malignant tumor.
出处
《南通大学学报(医学版)》
2011年第3期190-191,共2页
Journal of Nantong University(Medical sciences)
关键词
恶性肿瘤
凝血功能
妇科
mlignant tumor
coagulation function
gynecology