非酮症高血糖合并偏身舞蹈-投掷症

Non-ketotic hyperglycaemia with hemiballism-hemichorea

目的探讨非酮症高血糖合并偏身舞蹈-投掷症特征。方法对5例非酮症高血糖合并偏身舞蹈-投掷症患者的临床表现、实验室检查、影像学表现、治疗及预后进行回顾性分析。结果 5例均有突发持续、无目的、无节律的偏身舞蹈-投掷样不自主运动。血糖增高,但未发现酮体。头颅磁共振检查未见明显异常。应用胰岛素及氟哌啶醇药物治疗临床症状消失。结论非酮症高血糖可合并偏身舞蹈-投掷症。胰岛素及氟哌啶醇治疗效果好。

Objective To summarize the clinical characteristics of non-ketotic hyperglycaemia（NKHG） with hemiballism-hemichorea（HB-HC）.Methods Data of 5 cases with NKHG combined with HB-HC were retrospectively analyzed.Results All patients had the clinical manefestations of suddenly developed continuous,purposeless and arrhythmic HB-HC like involuntary movements.The patients had hyperglycaemia,but had no evidence of ketosis.The brain MRI showed no obvious abnormity.The clinical symptoms disappeared after pharmacological treatment with insulin and haloperidol.Conclusion NKHG can be associated with HB-HC,which can be treated effectively by insulin and haloperidol.